University of Hawai'i

Other

Pasteur Merieux Serums Et Vaccins

Sandra Chang

Tani Nishimura

Enzo Paoletti

Charles De Taisne

Kenton Kramer

George Hui

William Gosnell

Philip J Barr

Helen L Gibson

Wasim A Siddiqui

Wei-Wen Su

Robert Bugos

George S N Hui

Ann Hashimoto

David A Christopher

Benjamin Vine

Wasim A Siddigui

Compositions and methods are provided for the induction of a protective immunize response in primates against a lethal challenge of

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This invention is in the field of recombinantpolypeptides and relates to recombinant or synthetic antigen compositions which comprise p42 antigens, and more specifically to methods and compositions for the expression ofpolypeptides in transgenic plants.

Plasmodium falciparum merozoite surface protein-1 malaria produced in transgenic plants

Compositions and methods are provided for the induction of a protective immunize response in primates against lethal challenge of.

Baculovirus produced Plasmodium falciparum vaccine

The present invention provides compositions of matter comprising a polypeptide expressed from insect cells harboring a baculovirus vector the encodes the polypeptide, wherein the polypeptide comprises amino acid sequences derived from the p42 fragment of the gp 195 protein or derivatives thereof. Such compositions of matter find use for example for inducing the production of anti-p42 antibodies both in vivo and in vitro.

Baculovirus produced plasmodium falciparum vaccine

What is described is a recombinant poxvirus, such as vaccinia virus, containing foreign DNA from Plasmodium Merozoite Surface Antigen 1. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine.

Malaria recombinant poxvirus vaccine

Malaria recombinant poxvirus

Growing community of inventors

Honolulu, HI, United States of America

Sandra Chang