Dako A/s

S&oslash;ren &Oslash;stergaard

Arne Holm

Marianne Jartved Mathiesen

A diagnostic method is disclosed which utilizes short C-terminal fragments of sensu lato derived protein OspC. The 4 amino-terminal acids Pro-Lys-Pro (SEQ ID NO: 22) are shown to be essential in immune reactivity between sera from patients suffering from early borreliosis and various OspC derivatives and it is shown that in order to be effective as a diagnostic agent, 5 consecutive amino acid residues long homologue of a fragment identical to the 10 C-terminal amino acids of OspC (SEQ DI NO: 1). Also disclosed are vaccines utilizing the short peptides as well as methods for their preparation.

Growing community of inventors

Copenhagen, Denmark

Søren Østergaard

Growing community of inventors

Copenhagen, Denmark

S&oslash;ren &Oslash;stergaard

Søren Østergaard