Richter Gedeon Vegyeszeti Gyar Rt

Schering Aktiengesellschaft

Egis Gyogyszergyar Rt.

Sandor Solyom

Katalin Szilagyi Nee Farago

Ferenc Andrasi

Tamas Hamori

Pal Berzsenyi

Lajos Toldy

Janos Borvendeg

Istvan Tarnawa

Inge Schafer

Istvan Ling

Ilona Hermann Nee Szente

Marta Szollosy

Eleonora Szondy

Antal Simay

Melinda Gal

Gizella Abraham

Imre Moravcsik

Gabor Zolyomi

Istvan Pallagi

Katalin Eszter Horvath

Eszter Szentkuti

Katalin Horvath

Lajos Toldi

Emese Csuzdi

Ernese Csuzdi

Tibor Hasko

Franciska Erdo

Emese Csuzdl

Gabor Kapus

Erzsebet Birkas

Compounds of formula I are described, their production and use in pharmaceutical agents.

Condensed 2,3-benzodiazepine derivatives and their use as AMPA-receptor inhibitors

Derivatives of 2,3-benzodiazepine are substituted by one or two halogen atom(s) and have the general formula ##STR1## These derivatives are non-competitive AMPA antagonists and are used in pharmaceutical compositions. A process to make the 2,3-benzodiazepine derivatives includes converting starting compounds which are substituted by one or two halogen groups and have the general formula ##STR2##

2,3-Benzodiazepine Derivatives as non-competitive AMPA

3-substituted 3H-2, 3-benzodiazepine derivatives, the production and use

The invention relates to new pregnene derivatives of the general formula (I), ##STR1## wherein R.sup.1 stands for a C.sub.1-4 alkyl group;

Novel 20 benzcylamino pregnene derivatives and process for preparing same

New steroid-spiro-oxathiazolidine derivatives pharmaceutical compositions containing the same, and to a process for the preparation thereof are disclosed. The new compounds have antimineral corticoide effects and have the following formula (I), ##STR1## wherein R.sub.1 is a C.sub.1-3 alkyl or a C.sub.2-4 alkenyl group, and

Steroid-spiro-oxathiazolidine derivatives and a process for the

Compounds of the formula (I) having aldosterone-antagonizing activity are disclosed ##STR1## wherein R.sub.3 and R.sub.4 are each C.sub.1 to C.sub.3 alkyl; and

Substituted steroid-spiro-oxazolidinone derivatives and a process for

Diuretic pharmaceutically active steroid-spiro-oxazolidinone compounds of the formula (I), ##STR1## wherein R.sup.1 is hydrogen or methyl,

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Budapest, Hungary

Sandor Solyom