Mesoscale Technologies, LLC.

Singular Genomics Systems, Inc.

Siemens Healthcare Diagnostics Gmbh

Sandor L Kovacs

Eli N Glezer

Aaron H Leimkuehler

Bandele J Jeffrey-Coker

Charles M Clinton

George B Sigal

Jacob N Wohlstadter

Sudeep Kumar

Rodger Darin Osborne

Jules VanDersarl

Cecilia Zimmerman

Manish Kochar

David Marc Baranson

Kenneth E Page

Jon S Willoughby

Ian D Chamberlin

Leo Tabakin

Kristian Roth

Carl C Stevens

Christopher Frye

Michael L Vock

D T Le

Anson Hsu

John Van Doorn

Stephen Higgins

Gary I Krivoy

Yuji Ishitsuka

Carl Edens

Jaekyung Koh

Fei Yin

Sudeep M Kumar

Carl Stevens

George Sigal

Peter Louis Gebrian

Kerry Lynn Miller

Hu Cang

Michael Vock

Valeria Rascon

Frank Jay Robb

Pavel Shekhtmeyster

Robert James Stover

Pei-Ming Wu

Kevin Marshall

David Baranson

Dt Le

Greg Pinckney

Bandele Jeffrey-coker

Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format. Also disclosed are systems, devices, and methods provided herein for using a CCD camera based system to generate measurements having reduced crosstalk between measurements of multiple spatially separated subjects. CCD camera based systems as provided herein use improved reference level clamping circuits configured to fully reset reference levels during CCD readout, thereby reducing a level of crosstalk between measurements.

Assay apparatuses, methods and reagents including devices and methods for reducing crosstalk between CCD measurements

Disclosed herein, inter alia, are devices and methods for efficient transfer and analyses of cellular material, tissue samples, such as tissue sections.

Devices useful for sample manipulation

Instrument

Disclosed herein, inter alia, are devices, compositions, kits, and methods for interrogating biological samples.

Multiomic analysis device and methods of use thereof

Disclosed herein, inter alia, are devices and methods for efficient transfer and analyses of cellular material, tissue samples, such as tissue sections, using carrier substrates and devices.

Methods and devices for manipulating biological samples

Devices and methods for determining whether a contact of a liquid dispenser with a liquid based on sound and/or for determining a liquid volume in the liquid dispenser are provided. According to an embodiment, the liquid dispenser includes a sound generator and an acoustic sensor, and at least one of the sound generator or the acoustic sensor is disposed within the dispense chamber portion. According to an embodiment, the liquid dispenser includes a sound generator and an acoustic sensor, and further includes one or more side conduits, where at least one of the sound generator or the acoustic sensor is disposed within a cavity of a respective one of the one or more side conduits, wherein the cavity and a connector of each of the one or more side conduits are free from resonance within a frequency range of the sound sensed by the acoustic sensor.

Device and method for determining liquid contact and liquid volume in a liquid dispenser based on sound

A connector assembly is configured to fluidly and removably connect a first set of microtubes to a second set of microtubes of a microfluidic device. The connector assembly provides multiple points of contact to the microtubes to provide a secure connection between the connector assembly and the microtubes. A single gasket provides a securely aligned connection between microtubes.

Multiport disconnect couplings

We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.

Assay apparatuses, methods and reagents

A device comprising: a sample stage configured to be coupled to a microplate receiver; a microplate receiver configured to be coupled to a microplate; at least one heating element thermally coupled to the microplate receiver; a fluidics dispenser configured to dispense one or more reagents into the microplate; and an imaging system configured to detect one or more features in the microplate; and a structure physically coupled to the sample stage, the heating element, the fluidics dispenser, and the imaging system.

Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.

The present disclosure relates to a flow cell receiver. The flow cell receiver can include at least one platen, having a plurality of ports. The flow cell receiver can include magnets. The flow cell receiver can be configured to automatically align, secure, and retain a flow cell carrier containing a flow cell.

Flow cell receiver and methods of use

The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.

High throughput system for performing assays using electrochemiluminescence including a consumable shaking apparatus

Growing community of inventors

Middletown, MD, United States of America

Sandor L Kovacs