Richter Gedeon Vegyeszeti Gyar Rt

Stichting Rega Vzw

Richter Gedeon Vlcyeszeti Gyar Rt.

Sandor Gorog

Laszlo Szporny

Eva Palosi

Edit Toth

Jozsef Torley

Istvan Hajdu

Gyorgy Fekete

Csilla Meszaros

Szabolcs Szeberenyi

Pal Vittay

Imre Klebovich

Laszlo Vereczkey

Bela Kiss

Szaboles Szeberenyi

Erzsebet Lapis

Istvan Laszlovszky

Ferenc Auth

Szabolcz Szeberenyi

Csaba Szantay

Lajos Szabo

Masanori Baba

Tibor Keve

Erik D De Clercq

Lajos Dancsi

Zoltan Tuba

Dora Groo

Karola Jovanovics

Sandor Eckhardt

Eszter Dezseri

Janos Sugar

Katalin Honty

Sandor Holly

Jozsef Toth

Miklos Low

Laszlo Gaal

Miklos Nagy

Sandor Kerpel-Fronius

Sandorne Gyorgyi

Ivan Hindi

Egon Karpati

Gyorgy Hajos

Gabor T Szabo

Ferenc Trischler

Peter Aranyi

Aniko Gere

Istvan Horvath

Katalin Biro

Maria Marsai

Tibor Acs

Karoly Zalai

Tibor Cs

Anna Boor Nee Mezei

Eva Udvardy Nagy Nee Cserey Pechany

Csaba Molnar

Bulcsu Herenyi

Miklos Budai

Geza Wack

Bela Losonczi

Aniko Naray

Szabolcs Szebereneyi

Mate Kovatsits

Laszlo Csutoras

Erzsebet Francsics

Gabor Havasi

Anna M Boorne

Zsuzsanna Relle Nee Somfa

Zsuzsanna Relle Nee Somfai

Szabolos Szeberenyi

Laszlo Haal

Jozef Torley

Szaholes Szeberenyi

Groo

Erzsebet C Francsicsne

Steroids with pregnane skeleton, pharmaceutical compositions containing

Sulphated vinyl polymers such as sulphated polyvinylalcohol, sulphated copolymers of (meth)acrylic acid and vinylalcohol, and pharmaceutically acceptable salts thereof, have an antiviral effect against human immunodeficiency virus and may therefore be used as a therapeutic agent for treating retrovirus infections like AIDS and AIDS-related diseases. Their antiviral activity is apparently based on inhibition of virus adsorption; their inhibitory effect on giant cell formation is stronger than that of dextran sulphate.

Sulphated vinyl polymer in composition for treating retroviral infections

Sulphated vinyl polymers in compositions for treating retroviral

The invention relates to, therapeutically active 2-oxo-3,8-diazaspiro[4,5]decane derivatives (I), ##STR1## wherein R means hydrogen, a C.sub.1-12 alkyl, C.sub.3-6 cycloalkyl, carbocyclic C.sub.6-10 aryl or carbocyclic C.sub.6-10 aryl-C.sub.1-4 alkyl group, the latter two optionally being substituted on their aromatic moiety by one or more, same or different halogen(s) or one or more C.sub.1-4 alkyl or C.sub.1-4 alkoxy group(s);

2-oxo-3,8-diazaspiro(4,5)decane derivatives, pharmaceutical compositions

The invention relates to novel, therapeutically active 4-methylene-2-oxo-8-azaspiro[4,5]decane derivatives of the compound, ##STR1## wherein X means oxygen or an &gt;NR group, wherein

4-methylene-2-oxo-8-azaspiro[4,5]decane derivatives, pharmaceutical

The invention relates to novel, therapeutically active 4,4-disubstituted piperidine derivatives of the formula (I), ##STR1## wherein R.sup.1 means hydrogen or --CONHR group, wherein

4,4-disubstituted piperidine derivatives, pharmaceutical compositions

The invention relates to the novel 2,6-bis(chloromethyloxy-carbonyloxymethyl)pyridine of the formula (I) ##STR1## as well as a process for the preparation of this compound, which is a useful intermediate in the preparation of the anti-atherosclerotic 2,6-bis(hydroxymethyl)pyridine bis(N-methylcarbamate) (pyridinolcarbamate) and other drugs. According to the invention, the compound of the formula (I) is prepared by reacting 2,6-bis(hydroxymethyl)pyridine of the formula (II) ##STR2## with chloromethyl chloroformate of the formula (III) ##STR3## in a polar-aprotic, water-immiscible organic solvent, in the presence of a basic substance between about -30.degree. C. and +10.degree. C.

2,6-bis(chloromethyloxy-carbonyloxymethyl)pyridine and a process for

The invention relates to new aminoethoxybenzylalcohol derivatives of the formula (I) ##STR1## wherein R.sub.1 is hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms;

Aminoethoxybenzylalcohol derivatives, process for their preparation and

The invention relates to new dialkylaminoalkoxybenzylalcohol derivatives of the formula (I) ##STR1## wherein R.sub.1 is hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms;

Dialkylaminoalkoxybenzylalcohol derivatives, process for their

The invention relates to new aminopropanol derivatives of the formula (I) ##STR1## wherein R.sub.1 is halogen, trihalomethyl, alkoxy having from one to 3 carbon atoms or alkyl having from one to 3 carbon atoms,

1-(aminoalkoxyphenyl)-1-phenyl-propanols, process for their preparation

The invention relates to new 1,1-diphenylpropan-1-ol derivatives of the formula (I) ##STR1## wherein R.sub.1 and R.sub.2 independently represent hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms,

1,1-diphenylpropanol derivatives, process for their preparation and

The invention relates to the preparation of new diethylaminoalkoxybenzhydrol derivatives of the formula (I) ##STR1## wherein R.sub.1 is hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms,

Diethylaminoalkoxybenzhydrol derivatives, process for their preparation

The invention relates to new pyridine derivatives of the formula (I) ##STR1## wherein R.sub.1 and R.sub.2 independently represent hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms,

Certain-2-methyl-6-{4-[1-phenyl-1-hydroxypropyl]-phenoxymethyl}pyridines

The invention relates to the preparation of 3-trifluoromethyl- and 2,5-dimethyl-4'-hydroxy-.alpha.-ethyl-benzhydrol. Both compounds have so far been described only as metabolites of corresponding benzhydrol derivatives containing no hydroxyl group. Neither their physico-chemical characteristics nor their manufacturing processes have been disclosed in the known publications. 3-Trifluoromethyl- and 2,5-dimethyl-4'-hydroxy-.alpha.-ethyl-benzhydrol are suitable for the treatment of acute ethanolic intoxication. Accordingly, another aspect of the invention is a pharmaceutical composition containing one of these compounds as active ingredient.

Process for the preparation of 3-trifluoromethyl-and

The invention relates to new piperidine derivatives of the formula (I) ##STR1## wherein R.sub.1 is halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms; and

Piperidine derivatives and pharmaceutical compositions containing them

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Budapest, Hungary

Sandor Gorog