Unigen Corporation

Sandip K Nandy

Alexandre Mikhailovitch Nesterov

Carmen Hertel

Jiyun Liu

Abeysinghe Arrachchigae Papmapiya

Abeysinghe A Padmapriya

Teresa Horm

Kelly Rose Dawkins

Abeysinghe Arrachchigae Padmapriya

Compounds and methods related to the prevention and treatment of diseases and conditions, some of which are facilitated by melanogenesis are disclosed. Specifically, the present subject matter includes a series of compounds and compositions and their use for anti-melanogenic and antioxidant activity. This subject matter also includes the treatment of skin disorder due to acne vulgaris and related inflammatory and post inflammatory hyperpigmentation. Methods for synthesizing contemplated compounds are also disclosed.

Series of compounds for treatment of skin diseases and other conditions

The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.

Series of skin-whitening (lightening) compounds

Series of skin whitening (lightening) compounds

Compounds of structure (I): including stereoisomers, tautomers and salts thereof, wherein R, R, R, R, R, R, X, Y and Z are as defined herein. Such compounds are useful for the preparation of diarylpropane compounds. Methods for the preparation of compounds of structure (I) are also disclosed, as are methods employing compounds of structure (I) for the preparation of diarylpropanes.

Compounds and methods for preparation of diarylpropanes

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Olympia, WA, United States of America

Sandip K Nandy