Equifax Inc.

Asana Biosciences, LLC

Endo Pharmaceuticals Inc.

Libertas Bio, Inc.

Neharia Inc.

Sandeep Gupta

Tony Priestley

Nicholas James Laping

James Reid

Roger Astbury Smith

Lee Grice

Sudhakar Reddy

Scott Garten

Thresa Dixon

Dennis Horton

Shen Lu

Christian Hall

Scott Kevin Thompson

Ashis K Saha

Sonali Rudra

Wantanee Phuapradit

Sanjeeva P Reddy

Paras Jariwala

Matthew P Welsh

Helen Usansky

Louis Denis

Niranjan Rao

Aruna Railkar

David Zammit

Sharmistha Das

Shannon M Cothran

Anupy Singla Gupta

James R Reid

Shannnon M Cothran

Embodiments of the disclosure relate generally to formulations, methods of treatment, kits, and dosage forms for treating inflammatory disorders, including topic dermatitis, cancer, the formulations comprising an active pharmaceutical ingredient. The formulation provided comprises granules, wherein the granules comprise: micronized active ingredient; one or more granulation binders; one or more fillers; one or more disintegrants; and one or more antioxidants. In one embodiment, the methods of treatment include orally administering the active ingredient to a subject suffering from atopic dermatitis, where the active ingredient, is in an amount of about 20 mg to about 80 mg.

Formulations, methods, kits, and dosage forms for treating atopic dermatitis and for improved stability of an active pharmaceutical ingredient

This disclosure involves development and deployment platforms for decision algorithms. For example, a computing system provides software development interface to a client device. The system sets, based on an input from the client device via the interface, a decision engine to a test mode that causes the decision engine to operate on test data stored in a first database and that prevents the decision engine from applying operations from the client device to production data stored in a second database. The system also configures the decision engine in the test mode to execute a different decision algorithms on the test data. The system also sets, based on another input via the interface, the decision engine to a deployment mode that causes the decision engine to operate on the production data. The system configures the decision engine in the deployment mode to execute one or more of the tested decision algorithms.

Software development platform for testing and modifying decision algorithms

Disclosed are methods of treating cancer, which include administering a therapeutically effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt or ester thereof, to a subject in need thereof. Also disclosed are methods of inhibiting growth and proliferation of cancer cells in vitro or in vivo, which include contacting the cells with an amount of the compound of formula (I) effective to inhibit the growth or proliferation of the cancer cells. Further disclosed are methods of inhibiting tumor growth, which include contacting the tumor with an amount of the compound of formula (I) effective to inhibit the growth of the tumor.

Uses of pyrimido-pyridazinones to treat cancer

The present application provides methods of using the aminoindane compounds of formula (I) or (II) in treating an overactive bladder or interstitial cystitis by administering one or more of the compounds to a patient. 

Use of aminoindane compounds in treating overactive bladder and interstitial cystitis

The present application provides novel compounds and methods for preparing and using these compounds. These compounds are useful in treating pain, itch, overactive bladder and/or interstitial cystitis in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) and a TRPV1 receptor activator. In one embodiment, the TRPV1 receptor activator is lidocaine. 

Cyclohexylamines

Using natural language-like user inputs to provide statistics on a subset of data is described. In one embodiment, a user input that includes at least one word or phrase representing a rule is received. The rule includes an identification of a subset of data and a statistical expression to be performed on the subset of data. The subset of data includes at least part of the data elements of a data set. Each data element includes information on an individual or group. Instructions are provided for translating the rule into an executable format. The executable format includes a translated identification of the subset and a translated statistical expression. The subset of the data is accessed using the translated identification of the subset. The translated statistical expression is executed to obtain statistics on data elements of the subset of data. The statistics on the data elements are provided.

Systems and methods for managing statistical expressions

The present invention relates to application processing and decisioning systems and processes. One embodiment of the invention includes a method for automating decisioning for a credit request associated with an applicant. The method includes providing a user computer interface adapted to receive information associated with an applicant, and further adapted to display and receive information associated with at least one decision rule. The method also includes receiving information associated with an applicant through the user computer interface; receiving information associated with the applicant from at least one data source; and receiving a selection of information associated with a plurality of decision rules through the user computer interface. Furthermore, the method includes receiving a selection of rule flow information associated with the plurality of decision rules through the user computer interface; generating a plurality of decision rules based at least in part on the information associated with the applicant, based at least in part on the information associated with the applicant from at least one data source, and based at least in part on the selection of information associated with a plurality of decision rules, wherein an outcome associated with the at least one decision rule can be obtained; and based in part on at least the rule flow information, displaying at least a portion of the plurality of decision rules through the user computer interface.

Application processing and decision systems and processes

The present invention relates to automated decisioning for a credit request associated with an applicant. Information associated with an applicant is received. Data associated with the applicant is received from at least one data source. A user interface is configured to allow a user to provide a definition of decision rules in a near-natural language. Information associated with the decision rules is determined based on the definition of the decision rules. A selection of rule flow information associated with the decision rules is received through the user computer interface. A decision is generated based on the information associated with the applicant, data associated with the applicant from the at least one data source, the information associated with the decision rules, and the selection of information associated with decision rules. The decision is displayed.

Growing community of inventors

Plainsboro, NJ, United States of America

Sandeep Gupta