Novartis Ag

Advinus Therapeutics Private Limited

Sandeep Bhausaheb Bhosale

Debnath Bhuniya

Suresh Eknath Kurhade

Videsh Salunkhe

Mark G Bock

Gregory Raymond Bebernitz

Lili Feng

P Venkata Palle

Jessica Liang

Dumbala Srinivas Reddy

Vinod Vyavahare

Nadim S Shaikh

Atul Kashinath Hajare

Kasim A Mookhtiar

Keshav Naik

Venkata Poornapragnacharyulu Palle

Bhavesh Dave

Summon Koul

Anil M Deshpande

Santosh Kurhade

Sachin Kandalkar

Balasaheb Kobal

Siddhartha De

Gobind Sing Kapkoti

Ravikumar Velayutham

Debanath Bhuniya

Anil Deshpande

This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.

Glycoside derivatives and uses thereof

The present disclosure relates to a series of spirocyclic compounds of formula (I), their stereoisomers, tautomers, prodrugs, pharmaceutically acceptable salts, polymorphs, solvates, hydrates, N-Oxides, Co crystals and formulations thereof. The disclosure also relates to process of preparation of these spirocyclic compounds.  These compounds are useful in the treatment, prevention, prophylaxis, management, or adjunct treatment of all medical conditions related to inhibition of acyl CoA diacyl glycerol acyltransferase 1 (DGAT1).

Spirocyclic compounds, compositions and medicinal applications thereof

Acetamide derivatives, their stereoisomers, tautomers, prodrugs, pharmaceutically acceptable salts, polymorphs, solvates and formulations thereof for the prophylaxis, management, treatment, control of progression, or adjunct treatment of diseases and/or medical conditions where the activation of glucokinase would be beneficial, are disclosed.  The disclosure also provides process of preparation of these acetamide derivatives.

Acetamide derivatives as glucokinase activators, their process and medicinal application

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Pune, India

Sandeep Bhausaheb Bhosale