Tamkang University

San-Lang Wang

Van-Bon Nguyen

Yao-Haur Kuo

Anh-Dzung Nguyen

Hsin-Jen Chen

Po-Hao Shih

A composition for inhibiting &#x3b1;-glucosidase has lower side effects to a user, other than the inhibition of &#x3b1;-glucosidase. The composition comprises adenine, (3-hydroxy-dl-proline, nicotinic acid, (3,6-dioxo-piperazin-2-yl)-acetic acid amide, 2-ethylhexyl heptanoate, and a pharmaceutically compatible salt.

Pharmaceutical composition for inhibiting alpha-glucosidase

A method for producing alpha-glucosidase inhibitors utilizingsp., wherein utilizing asp. strain which is deposited at Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH (DSMZ) and numbered No. DSM 32521 to produce the alpha-glucosidase inhibitors, thesp. Strain is cultivated in a commercial culture medium or a shrimp/crab residue-contained culture medium, and the alpha-glucosidase inhibitors is separated from a fermented supernatant. The alpha-glucosidase inhibitors have strong inhibitory activity.

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Asp. strain TKU015 is deposited under DSMZ GmbH (Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH) Number DSM 21747). Thesp. strain TKU015 can be used to produce chitinase, chitosanase and nattokinase. A method of producing chitinase, chitosanase and nattokinases can use thesp. strain TKU015.

Growing community of inventors

Taipei, Taiwan

San-Lang Wang