Columbia University

International Business Machines Corporation

Other

Samuel Jonas Wind

Sandip Tiwari

Jinyao Tang

James Hone

Jeffrey William Kysar

Stephen O'Brien

Limin Huang

Michael P Sheetz

Ruben L Gonzalez, Jr

Porter Dean Gerber

Brian Edward White

Jinyu Liao

Colin Kinz-Thompson

Manus J P Biggs

Teresa Anne Fazio

Matteo Palma

Alexander Alexeevich Godarenko

Ryan Cooper

Carl Fredrik Oskar Dahlberg

Daniel Alexandre Chenet

An elastomeric substrate comprises a surface with regions of heterogeneous rigidity, wherein the regions are formed by exposing the elastomeric substrate to an energy source to form the regions such that the regions include a rigidity pattern comprising spots.

Cellular response to surface with nanoscale heterogeneous rigidity

The disclosed subject matter provides a nanoaperture having a bottom surface and a side wall comprising gold. A surface of the side wall is passivated with a first functional molecule comprising polyethylene glycol. The bottom surface of the nanoaperture can be functionalized with at least one second molecule comprising polyethylene glycol, for example, a silane-PEG molecule. The second molecule can further include a moiety, such as biotin, which is capable of binding a target biomolecule, which in turn can bind to a biomolecule of interest for single molecule fluorescence imaging analysis. Fabrication techniques of the nanoaperture are also provided.

Functionalized surfaces and methods related thereto

Apparatus and methods for forming the apparatus include nanoparticles, catalyst nanoparticles, carbon nanotubes generated from catalyst nanoparticles, and methods of fabrication of such nanoparticles and carbon nanotubes.

Preparing nanoparticles and carbon nanotubes

The present invention is directed to a device comprising (a) a substrate having a surface and (b) an ordered array of posts over the surface, wherein the posts are capable of binding a protein or small molecule ligand, and wherein the pitch between adjacent posts is less than about 100 nm. The invention is also directed to methods for identifying the presence of an analyte in a fluid and to methods for measuring relative binding specificity or affinity between an analyte in a fluid and the posts, using the device of the present invention.

Device for measuring nanometer level pattern-dependent binding reactions

The present invention relates to methods for fabricating nanoscale electrodes separated by a nanogap, wherein the gap size may be controlled with high precision using a self-aligning aluminum oxide mask, such that the gap width depends upon the thickness of the aluminum oxide mask. The invention also provides methods for using the nanoscale electrodes.

Methods of fabricating electrodes and uses thereof

Methods for fabricating nanoscale electrodes and uses thereof

A method for formulating an exposure dose for an electron beam on a resist film for a pattern of geometric shapes which compensates for electron scattering effects utilizing hierarchial design data which is preserved to as great as an extent as possible in the computation of the exposure dose. The exposure dose is corrected for both the forward scatter and backscatter effects of the electron beam in which the design data is modified for interactions of shapes which are affected only over the forward scatter range. In another version of the method, a multiple Gaussian approximation is used where the short term Gaussian terms are treated as the forward scatter terms and the long term Gaussian terms are treated as the back scatter terms.

Electron beam proximity correction method for hierarchical design data

A dual gate field effect transistor with an ultra thin channel of substantially uniform width formed by a self-aligned process utilizing selective etching or controlled oxidation between different materials to form a vertical channel extending between source and drain regions, having a thickness in the range from 2.5 nm to 100 nm.

Self-aligned dual gate MOSFET with an ultranarrow channel

Method of making self-aligned dual gate MOSFET with an ultranarrow

Growing community of inventors

White Plains, NY, United States of America

Samuel Jonas Wind