Massachusetts Institute of Technology

Samuel Gordon Rodriques

Edward Stuart Boyden

Adam H Marblestone

Fei Chen

Mark Andrew Skylar-Scott

Ruixuan Gao

Paul Warren Tillberg

Daniel Oran

Shoh Asano

The invention, in part, includes methods of single molecule protein sequencing that include using weak binding spectra in the amino acid identification.

Single molecule peptide sequencing methods

The present invention enables three-dimensional nanofabrication by isotropic shrinking of patterned hydrogels. A hydrogel is first expanded, the rate of expansion being controlled by the concentration of the crosslinker. The hydrogel is then infused with a reactive group and patterned in three dimensions using a photon beam through a limited-diffraction microscope. Functional particles or materials are then deposited on the pattern. The hydrogel is then shrunk and cleaved from the pattern.

Three-dimensional nanofabrication by patterning of hydrogels

Growing community of inventors

Cambridge, MA, United States of America

Samuel Gordon Rodriques