Melchior Material and Life Science France

M2i Development

Ceva Sante Animale

Virbac Corporation

M2i Salin

Samuel Dufour

Olivier Guerret

Patricia Monginoux

Hafid Belhadj-Tahar

Loic Guilloneau

Loic Guilonneau

Loic Guillonneau

Valérie LeJeune

Hubert Sevestre

The present invention describes a new technology for the formulation of semiochemicals in wick diffusers particularly effective in controlling the diffusion of semiochemicals over periods of several months regardless of the outside temperature.

Controlled-diffusion semiochemical composition

The present invention describes new formulations of semiochemical compounds for mammals in wick diffusers particularly effective in controlling the diffusion of several semiochemicals having different volatilities over long periods of time and independently of the temperature and humidity conditions.

Temperature-controlled semiochemical composition diffusers

The invention relates to novel soothing compositions for animals, particularly for cats. It specifically relates to soothing compositions for non-human mammals, comprising between 1% and 50% w/w of at least one fatty acid comprising between 5 and 22 carbon atoms and between 0.01% and 5% w/w of nepetalactone, such that said at least one fatty acid and said nepetalactone are dissolved in a solvent. Said compositions are characterised in that they exhibit soothing properties for stressed animals and are stable for the entire period of use thereof.

Soothing composition for animals, comprising at least one fatty acid and nepetalactone

The invention relates to paintball-pellet-type projectiles containing insect pheromones encapsulated in an aqueous oil-in-water-type formulation. Said formulations can release said pheromones in a sustained manner. Said projectiles are characterised in that they contain the aqueous formulation of encapsulated pheromone compatible with the envelope of the projectile composed of oxo-degradable polymer. The aim of the invention is to use said projectiles to treat trees against insect pests by spraying and bursting said projectiles on the trunks of said trees.

Oxo-degradable projectiles containing pheromones

The present invention is directed towards microparticles consisting of a solid shell made of polymer, in particular an acrylic polymer, surrounding a core comprising a mixture of oil and wax and also pheromone. The present invention is also directed towards a production process and the use of an aqueous suspension of such microparticles containing pheromones comprising fatty chains, such as lepidopteran pheromones, and which are capable of releasing the pheromones in a sustained manner.

Particles containing pheromones and production process

The invention relates to a compound of general formula (I) (in configuration Z or E) and to pro-pheromonal compositions and formulations comprising said compound, in addition to the uses thereof for soothing purposes for non-human mammals such as sheep, pigs, sheep, cattle, felines, equines and canines. 

Soothing pro-pheromonal composition for mammals

The present invention concerns a method to access (E,Z)-7,9-dodecadienyl-1-acetate in two synthesis steps with excellent yields and selectivity greater than 70% by transformation of 2-hexenal into a novel intermediate, which is itself then transformed into (E,Z)-7,9-dodecandienyl-1-acetate.

Method for producing (E,Z)-7,9-dodecadienyl-1-acetate

The subject matter of the present invention is the novel molecules of formulae E, E' and F. These molecules prove to be synthesis intermediates that are very advantageous for the manufacture of derivatives of sphingosine or of ceramides functionalized in position 1, with good yields, in which Rand Rare fatty chains, Ris an alkyl group and Ris a protective group for alcohol functions. Another subject of the invention is the use of the intermediates of type F for converting same into intermediates of type G, by means of reduction in the presence of lithium borohydride. The G molecules are precursors that are known to make it possible to obtain sphingolipids or sphingomyelin.

Synthesis intermediates for obtaining derivatives of sphingosines, ceramides and sphingomyelins with good yields

The present invention concerns novel chemical compounds corresponding to formulae (I) and (II): (I) (II) which, when marked with fluorine-18, can be used as markers of NMDA receptors for carrying out studies with a scanner.

Chemical compounds derived from normemantine and use of same in the medical field

The present invention relates to a process for preparing sordidin, comprising a step of preparing 4-(2-ethyl-1,3-dioxolan-2-yl)pentan-2-one by means of a reaction in which 2-ethyl-2-(pent-4-en-2-yl)-1,3-dioxolane is oxidized in the presence of a catalyst chosen from the group comprising organometallic complexes of transition metals.

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Orthez, France

Samuel Dufour