Chdi Foundation, Inc.

Samuel Coe

Celia Dominguez

Michael Edward Prime

Jonathan Bard

John Wityak

Peter David Johnson

Christopher John Brown

Daniel Clark-Frew

Sarah Hayes

Thomas Martin Krulle

Thomas Martin Krülle

Matthew Robert Mills

Richard Waldron Marston

Alex Kiselyov

Sébastien René Gabriel Galan

Paul Richard Giles

Duane Higgins

Samantha Brown

Longbin Liu

Matthew Randolf Lee

Elise Luciennen Paulette Gadouleau

Elise Lucienne Paulette Gadouleau

Sebastien Rene Gabriel Galan

Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.

Probes for imaging huntingtin protein

The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.

Compounds for targeting mutant huntingtin protein and uses thereof

Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use. 

Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use. 

Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use 

Probes for imaging Huntingtin protein

Growing community of inventors

Northampton, United Kingdom

Samuel Coe