Labcyte Inc.

Dh Technologies Development Pte. Ltd.

Mobius Biomedical, Inc.

Enquyst Technologies Inc.

Folde Inc.

Sammy S Datwani

John R Linton

Don Wesley Arnold

Stephen J Hinkson

Jason M Criscione

Lucien P Ghislain

Eric Sackmann

Ali Ersen

Chang Liu

Richard G Stearns

Marsha N Blauwkamp

Carson Riche

Justin Blonigan

Thomas Covey

John P Lunsford

Thomas R Covey

Robert Steven Bley

Young M Kang

MingYao Ding

Donald W Arnold

Methods of ejecting droplets containing a non-Newtonian fluid by an acoustic droplet ejector can include applying a tone burst of focused acoustic energy to a fluid reservoir containing a non-Newtonian fluid at sufficient amplitude to effect droplet ejection according to a tone burst pattern. The tone burst pattern may include three discrete tone burst segments, the first tone burst segment having greater duration than the second and third segments, and third segment having greater duration than the second segment. The exact durations and amplitudes of the tone burst segments can be tuned to influence the ejection properties.

Acoustic droplet ejection of non-newtonian fluids

Embodiments of the present invention provide systems and methods for tagging and acoustically characterizing containers.

Systems and methods for tagging and acoustically characterizing containers

A system and method are provided for loading a sample into an analytical instrument using acoustic droplet ejection ('ADE') in combination with a continuous flow sampling probe. An acoustic droplet ejector is used to eject small droplets of a fluid sample containing an analyte into the sampling tip of a continuous flow sampling probe, where the acoustically ejected droplet combines with a continuous, circulating flow stream of solvent within the flow probe. Fluid circulation within the probe transports the sample through a sample transport capillary to an outlet that directs the analyte away from the probe to an analytical instrument, e.g., a device that detects the presence, concentration quantity, and/or identity of the analyte. When the analytical instrument is a mass spectrometer or other type of device requiring the analyte to be in ionized form, the exiting droplets pass through an ionization region, e.g., an electrospray ion source, prior to entering the mass spectrometer or other analytical instrument. The method employs active flow control and enables real-time kinetic measurements.

System and method for the acoustic loading of an analytical instrument using a continuous flow sampling probe

Described herein are various embodiments of flexible catheters comprising one or more flexibility regions. In one embodiment, a catheter comprises an elongate body having a proximal segment and a distal segment; a first lumen defined by the elongate body and configured for drainage of a liquid from a bodily region; and a plurality of flexibility regions on or in the distal segment of the elongate body. The plurality of flexibility regions, collectively, is configured to passively bend anteriorly. Further, at least one of the plurality of flexibility regions has a defined percent volume of material removed and a defined cut depth percentage. The features and arrangement of the flexibility regions described herein result in the catheter requiring reduced force during insertion into a bodily lumen.

Flexible catheters and related methods

Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Process technology for biological product manufacturing and downstream purification

Growing community of inventors

Pleasanton, CA, United States of America

Sammy S Datwani