Rhodia Chimie

Roussel Uclaf

Rhone-poulenc Chimie

Les Laboratoires Servier

Ilypsa, Inc.

Centre National De La Recherche Scientifique

Les Laboratories Servier

Ecole Polytechnique

Xanchem

Samir Z Zard

Dominique Charmot

Mathias Destarac

Béatrice Sire

Gérard Mignani

Pascale Corpart

Jean Boivin

Christine Chauvet

Mehdi Boumediene

Chakib Kalai

Han Ting Chang

Derek H Barton

Fabien Gagosz

Ghenwa Bouhadir

Lucie Tournier

Zofia Agnieszka Wilczewska

Eric B Henriet

Hervé Adam

Isabelle Gauthier-Gillaizeau

Xavier Franck

Beatrice Sire

Thibaud Biadatti

Philippe Jost

William B Motherwell

Daniel Michelet

Jocelyne Wozniak

Chakib KalaÏ

Process for the industrial synthesis of the compound of formula (I)

Process for the synthesis of agomelatine

Process for the industrial synthesis of the compound of formula (I) 

The invention relates to compounds having the general formula (I), the method of preparation thereof and the use thereof in organic radical synthesis. The invention also relates to compounds having the formula (II), the method of preparation thereof and a method for preparing compounds having the formula (VIII). 

Compounds comprising a thiocarbonyl-sulfanyl group which can be used for the radical synthesis of &#x3b1;-perfluoroalkylamine compounds

The present invention relates to a method for partial or total oxidation of one or several thiocarbonylthio ends of a polymer, obtained by radical polymerisation controlled by reversible addition-cleavage with thiocarbonylthio agents, Said method comprising the step of contacting said polymer with an ozone-containing gas, during which ozone reacts with the one or several thiocarbonylthio ends.

Method for partial or total oxidation of one or several thiocarbonylthio ends of a polymer obtained by radical polymerisation controlled by reversible addition-fragmentation

Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-&#x3b1;-perfluoroalkylamines

The invention concerns a method for preparing polymers having at least a thiol function, comprising pyrolysis of at least a polymer having at least a function of formula (I), wherein: R1, R2, R3 and R4 are such as defined in the description 

Method for synthesis of polymers with thiol functions

The present invention provides polymeric and pharmaceutical compositions comprising a polymer that contains vicinal amine moieties, referred to as polyvicinalamine polymers. The polyvicinalamines can be copolymers or homopolymers. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of renal diseases, hyperphosphatemia, and the removal of bile acids, oxalates and iron from the gastrointestinal tract.

Polyamine polymers

A polymer composition and method of preparing same is described wherein an ethylenically unsaturated monomer is contacted with a source of free radicals and a compound of formula (1A), (1B) and (1C) as defined herein. The polymer composition may be a homopolymer or a block copolymer.

Synthesis method for polymers by controlled radical polymerisation with xanthates

The invention concerns a method for preparing a polymer, comprising a step which consists in contacting: (A) at least a living organic polymer having at its chain end a dithiocarbonylated or dithiophosphorylated function capable of being reactivated; (B) at least a source of free radicals; and (C) at least an organic compound bearing a labile hydrogen atom, whereby the dithiocarbonylated or dithiophosphorylated function present on said living organic polymer is substituted by a hydrogen atom.

Method for free radical reduction of dithiocarbonylated or dithiophosphorylated functions borne by a polymer

The invention concerns a method for preparing by thermal activation of hybrid silicone and organic polymers comprising the motifs RxUySiO[4&#x2212;(x+y)]/2 (I) wherein: x is equal to 0, 1, 2 or 3, y is equal to 0, 1, 2 or 3 with 2&#x2266;(x+y)&#x2266;3 and y is different from 0 for at least one of the hybrid copolymer motifs; and the symbols U, identical or different, represent organic polymer units.

Method for synthesis of hybrid silicon and organic copolymers by controlled free radical polymerization

Chain end functionalized block copolymers having low polydispersity index are produced via controlled free radial polymerization of dithiocarbamates.

Method for block polymer synthesis by controlled radical polymerization from dithiocarbamate compounds

The invention concerns a method for preparing polymers, characterised in that it consists in contacting: at least an ethylenically unsaturated polymer, at least a source of free radicals, and at least a compound of general formula (IA) wherein R represents a group formula (I); R being advantageously an electron-attracting group.

The invention concerns a method for preparing polymers, which consists in contacting: an ethylenically unsaturated monomer; a soure of free radicals; and a halogenated xanthate.

Growing community of inventors

Gif-sur-Yvette, France

Samir Z Zard