Societe Des Produits Nestle S.a.

Glycom A/s

Sami Damak

Norbert Sprenger

Francis Foata

Bruce McConnell

Louise Kristine Vigsnæs

Florence Rochat

Clara Lucia Garcia-Rodenas

Andreas Rytz

Jane Mea M Natividad

Claire Laurence Lucie Marie Boulange

The present invention relates to nutritional compositions comprising 2'-Fucosyllactose (2′FL) for use in improving the gastrointestinal barrier. In particular, the present invention relates to improving gastrointestinal barrier in an infant, a young child or children aged above 3 years to 8 years.

Nutritional composition comprising 2'-Fucosyllactose (2′ FL) to improve the gastrointestinal barrier

The present invention relates to nutritional compositions comprising 6'-sialyllactose (6′SL) and lacto-N-tetraose (LNT) for use in improving the gastrointestinal barrier. In particular, the present invention relates to improving gut barrier function in an infant, a young child or children aged above 3 years to 8 years.

Nutritional composition comprising 6'SL and LNT in combination to improve the gastrointestinal barrier function

Compositions contain 6'-sialyllactose (6′ SL) and lacto-N-tetraose (LNT), for use in the reduction of nociception in an infant or in a young child. The compositions are in particular useful in reducing abdominal pain, such as pain associated with infantile colic, irritable bowel syndrome (IBS) and/or recurrent abdominal pain (RAP), and consequently also contribute to reducing the crying periods and to improving the quality of sleep and the general quality of life of the infants and young children.

Compositions for use in the reduction of nociception in children

The present invention relates to compositions comprising 6'-sialyllactose (6&#x2032;SL) and lacto-N-tetraose (LNT), for use in the reduction of nociception in an infant or in a young child. The compositions are in particular useful in reducing abdominal pain, such as pain associated with infantile colic, irritable bowel syndrome (IBS) and/or recurrent abdominal pain (RAP), and consequently also contribute to reducing the crying periods and to improving the quality of sleep and the general quality of life of the infants and young children.

Compositions for use in the reduction of nociception in infants and young children

The application relates to synthetic compositions and methods for preventing or reducing nociception and/or nociceptive sensitivity in a non-infant human. The human is administered a composition comprising 6'-sialyllactose (6&#x2032;-SL) and/or lacto-N-tetraose (LNT).

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Lausanne, Switzerland

Sami Damak