Theranos, Inc.

Labrador Diagnostics LLC

Phillips 66 Company

Theranos IP Company, LLC

Samartha Anekal

Elizabeth A Holmes

Daniel L Young

Chinmay Pangarkar

Timothy Robert Smith

Mark Dayel

James Richard Wasson

Karan Mohan

Ian Gibbons

Paul Patel

Gary Frenzel

John Kent Frankovich

Michael Kerby Chen

Joy Roy

Deborah Sloan

Alexander Loo

Adrit Lath

Sunny Balwani

Timothy Smith

Swapna Joshi

In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

Systems and methods for analyte testing and laboratory oversight

Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Systems and methods for fluid handling

Systems and methods for sample handling

Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data.

Rapid measurement of formed blood component sedimentation rate from small sample volumes

Methods, devices, systems, and apparatuses are provided for the image analysis of measurement of biological samples.

Image analysis and measurement of biological samples

Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 &#x3bc;L) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.

Low-volume coagulation assay

Systems and methods for multi-analysis

In one embodiment described herein, a cartridge is provided comprising a cartridge frame; a plurality of diluents each in an expandable container; a plurality of reagents each in an expandable container; and a plurality of mixing vessels comprising empty expandable containers.

Methods and devices for small volume liquid containment

The devices and systems disclosed herein provide multiple optical capabilities in a single device or system. Methods for using these devices and systems are provided. These devices and systems are configurable for operation in each of a spectroscopy mode, a fluorescence mode, and a luminescence mode, and are capable of performing spectroscopic, fluorescence, and luminescence observations, measurements, and analyses when operated in the corresponding spectroscopy mode, fluorescence mode, or luminescence mode. These devices and systems include mirror dispersion elements having multiple faces including an optical dispersion element on one face (e.g., a diffraction grating or a prism) and a reflective element on another face (e.g., a mirror). These multiple capabilities eliminate the need to move or load a sample in multiple devices when subjecting a sample to multiple analyses, and thus provide greater accuracy, precision, and speed while reducing complexity and cost of sample analysis.

Unified detection system for fluorometry, luminometry and spectrometry

In one embodiment described herein, a bodily fluid separation material is provided comprising a formed component capture region and a bodily fluid pass-through region. The pass-through region has structures with a reduced liquid leaching quality relative to than the capture region, wherein during separation material use, bodily fluid enters the capture region prior to entering the pass-through region. Optionally, a bodily fluid pass-through region has a reduced amount of liquid leaching material relative to than the capture region.

Systems, devices, and methods for bodily fluid separation materials

Growing community of inventors

Palo Alto, CA, United States of America

Samartha Anekal