Continuus Pharmaceuticals, Inc.

Massachusetts Institute of Technology

Continuus Pharmeceuticals, Inc.

Salvatore Mascia

Stephen C Born

Bayan T Takizawa

Joshua Dittrich

Won Sik Kim

Trevor Alan Hatton

Bernhardt Levy Trout

Allan Stuart Myerson

Gregory C Rutledge

Yi Du

Jung-Hoon Chun

Nikhil Padhye

Keith M Forward

Himanshu Hemant Dhamankar

Emily Chang

James M B Evans

Ryan Richard Slaughter

Erica Marie Bortoff

Mao Wang

Blair Kathryn Brettmann

Ethan Disston Penner

James Mb Evans

Joshua V Dittrich

The present disclosure provides for a continuous rotary plate filter apparatus and a method of using the apparatus to separate slurries into liquids and solids. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.

Continuous rotary plate filter and methods of use thereof

The present disclosure provides for a continuous membrane separator bypass system and a continuous filtration separator system and methods of using the systems in the separation of liquid-liquid mixtures and filtration of process liquids. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.

Continuous separator bypass systems and methods of use thereof

The present disclosure provides for a continuous drying apparatus and a method of using the apparatus in the preparation of dried solids from slurries. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.

Continuous drum dryer and methods of use thereof

Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet.

Layer processing for pharmaceuticals

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Boston, MA, United States of America

Salvatore Mascia