Fenwal, Inc.

Other

Ecolab USA Inc.

Corpak Medsystems, Inc.

Microtek Medical Inc.

Stackhouse, Inc.

Salvatore Manzella, Jr

Gregory G Pieper

Steven R Katz

Brian C Case

Kyungyoon Min

Richard L West

Terry Chung

Michael C Shaughnessy

David K Platt

Mark B Jones

Kevin T Pullen

Alison J Sanders

Keith A Larson

Natalie Osterweil

Christopher Zachara

Shawn G Purnell

Alan R Shapiro

Donald A Kay

Patrick Flanagan

Mark Witt

David S Jaggi

King Y Moy

Joseph P Killam

Greg Pieper

William Henry Cork, Iii

Katherine N Radwanski

Daryl Richard Calhoun

Timothy Getschman

Brain C Case

Benjamin Rockwell

Daryl Calhoun

Fluid separation chambers are provided for rotation about an axis in a fluid processing system. The fluid separation chamber may be provided with first and second stages, with the first and second stages being positioned at different axial locations. In another embodiment, at least one of the stages may be provided with a non-uniform outer diameter about the rotational axis, which may define a generally spiral-shaped profile or a different profile for fractionating a fluid or fluid component. One or more of the stages may also have a varying outer diameter along the axis. The profile of the chamber may be provided by the chamber itself (in the case of rigid chambers) or by an associated fixture or centrifuge apparatus (in the case of flexible chambers).

Centrifuges and centrifuge inserts for fluid processing systems

Fluid separation chambers for fluid processing systems

One embodiment relates to a pressure sensor apparatus, including a housing with a flexible member and an aperture configured to receive a fluid. The pressure sensor apparatus further includes a first member disposed on the flexible member, a second member removably coupled to the first member configured to move in response to a pressure of the fluid and a sensor configured to detect the movement of the second member. The pressure sensor apparatus generates a pressure signal for the fluid based on the displacement of the second member.

Apparatus with rigid member for sensing fluid pressure

A sheeting is provided for use with a fluid processing cassette having a valve station with a plurality of fluid flow ports. The sheeting has a generally flexible layer and a biasing member associated with the layer. The sheeting is attached to the cassette such that the biasing member is received within the valve station. The cassette may be used with a fluid processing system having a valve actuator with a piston that is aligned with the cassette during use. In an extended position, the piston presses the sheeting against the port to prevent fluid flow through the valve station. When the piston moves from the extended position to a retracted position, it allows the sheeting to uncover the port, thereby allowing fluid flow through the valve station. The biasing member assists in displacing the sheeting from the port when the piston moves to the retracted position.

Spring-open sheeting for fluid processing cassette

Centrifuges are provided for rotating fluid separation chambers about an axis in a fluid processing system. The centrifuge may be provided with high- and low-G walls, with a gap defined between the high- and low-G walls. A first section of the gap may have a substantially uniform radius about the axis, while a second section of the gap may have a non-uniform radius about the axis. The radius of the second section of the gap about the axis at all locations is no larger than the radius of the first section of the gap about the axis. The high-G wall may comprise an inner surface of an outer bowl, while the low-G wall may comprise an outer surface of an inner spool. At least a portion of the second section of the gap may have a varying radius along the axis and/or be configured as a spiral.

Bearing for umbilicus of a fluid processing system

An irradiation device includes a fluid treatment chamber configured to receive a biological fluid container, the fluid treatment chamber having opposing first and second sides, at least one light source disposed adjacent at least one of the first and second sides of the fluid treatment chamber, and an overflow reservoir in fluid communication with the fluid treatment chamber to receive fluid leaking from the biological fluid container. The device also includes a non-contact sensor disposed adjacent the overflow reservoir and configured to generate a signal according to leaked fluid in the overflow reservoir, an indicator, and a controller coupled to the at least one light source, the non-contact sensor and the indicator, the controller configured to activate the indicator upon receipt of the signal from the sensor and to deactivate the at least one light source subsequent to receipt of the signal from the sensor.

Systems and methods for detecting fluid leaks using a non-contact sensor

A fluid circuit for use with a fluid processing assembly, the fluid circuit comprising an umbilicus having a first end, a second end, an axis of rotation, and a cross-sectional circumference; a one-piece bearing secured to the umbilicus at a location between the first and second ends, the bearing having an axis of rotation and including an inner lumen which directly engages the umbilicus and includes a plurality of traction features, which bear against the umbilicus to prevent relative rotation of the bearing and the umbilicus; and the plurality of traction features comprising a first traction feature configured to engage the umbilicus at a first set of lengths between the first and second ends and a second traction feature configured to engage the umbilicus at a second set of lengths between the first and second ends.

A medical device position guidance system having a noninvasive medical device communicable with an invasive medical device. The system provides outputs useful to assess the position of an invasive medical device in an animal, such as a human. A magnetic field is used to gather information about the position of the invasive device. Radio waves are used to communicate this information between the noninvasive device and the invasive device.

Medical device position guidance system with wireless connectivity between a noninvasive and an invasive device

A fluid circuit for use with a fluid processing assembly, the fluid circuit comprising an umbilicus having a first end, a second end, an axis of rotation, and a cross-sectional circumference; a one-piece bearing secured to the umbilicus at a location between the first and second ends, the bearing having an axis of rotation and including an inner lumen which directly engages the umbilicus and includes a plurality of traction features, which bear against the umbilicus to prevent relative rotation of the bearing and the umbilicus; and the plurality of traction features comprising a first traction feature configured to engage the umbilicus at a first length between the first and second ends and a second traction feature configured to engage the umbilicus at a second length between the first and second ends.

One embodiment relates to a pressure sensor apparatus, including a housing with a flexible member and an aperture configured to receive a fluid. The pressure sensor apparatus further includes a first member disposed on the flexible member, a second member removeably coupled to the first member configured to move in response to a pressure of the fluid and a sensor configured to detect the movement of the second member. The pressure sensor apparatus generates a pressure signal for the fluid based on the displacement of the second member.

Apparatus with flexible member for sensing fluid pressure

A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly () about a first axis at a first angular velocity and rotating the chamber assembly () coaxially with the yoke assembly at a second angular velocity A drive motor () is provided for rotating the yoke assembly at the first angular velocity A stationary gear () is mounted coaxially with the yoke assembly, with a drive linkage () comprising a shaft () secured to the yoke assembly so as to be rotatable therewith. The shaft is operatively connected on its first end to the stationary gear (), so that the shaft rotates about its axis as the yoke assembly () rotates relative to the stationary gear. The shaft () is rotatably connected on its second end to the chamber assembly (), so that when the shaft is rotated, the shaft rotates the chamber assembly. Preferably, the yoke assembly () comprises a first arm () and a second arm (), with the chamber assembly () being rotatably secured to the first arm and the first arm being pivotably connected to the second arm, and the shaft () being flexible.

Flexible shaft drive system for centrifuge with pivoting arms

A drive assembly for a centrifugal processing system is provided for rotating the yoke assembly () about a first axis at a first angular velocity and rotating the chamber assembly () coaxially with the yoke assembly at a second angular velocity A drive motor () is provided for rotating the yoke assembly at the first angular velocity and simultaneously rotating the chamber assembly at the second angular velocity by a sun gear () mounted to the chamber assembly for rotation about the first axis and a planetary gear () mounted to the yoke assembly that is operatively connected to the sun gear such as to impart rotation to the sun gear as it orbits thereabout upon rotation of the yoke assembly.

Drive system for centrifuge with planetary gear and flexible shaft

Growing community of inventors

Barrington, IL, United States of America

Salvatore Manzella, Jr