Suntory Limited

Suntory Holdings Limited

Ajinomoto Co., Ltd.

Kaneka Corporation

Kyoto University

Nippon Zeon Company, Ltd.

Roche Vitamins Inc.

Novartis Ag

Other

Toyota Jidosha Kabushiki Kaisha

Dsm IP Assets B.v.

Nitto Chemical Industry Co., Ltd.

Kanegafuchi Chemical Industry Co., Ltd.

Lonza Ag

Nippon Suisan Kaisha, Ltd.

Sakayu Shimizu

Hideaki Yamada

Kengo Akimoto

Jun Ogawa

Hiroshi Kawashima

Yoshifumi Shinmen

Michihiko Kataoka

Kenichi Higashiyama

Masaru Wada

Keiji Sakamoto

Yoshiki Tani

Michihiko Kobayashi

Yoshihiko Yasohara

Yury Ivanovich Kozlov

Noriyuki Kizaki

Sergey Vasilievich Smirnov

Veronika Aleksandrovna Kotliarova

Tomohiro Kodera

Shozo Shiozaki

Makoto Hibi

Natalia Nikolaevna Samsonova

Natalia Yurievna Rushkevich

Shigenobu Kishino

Yasunori Yonejima

Yoshihide Suwa

Michihiro Sugano

Eiji Sakuradani

Toshiaki Yaguchi

Satomi Takahashi

Junzo Hasegawa

Masayoshi Muramatsu

Sumio Asami

Kazuyoshi Yajima

Yukio Yamada

Shusei Obata

Yasuhiro Ikenaka

Hirokazu Nanba

Masayuki Takano

Shigeaki Fujikawa

Souichi Morikawa

Tadanori Morikawa

Vitaly Grigorievich Paraskevov, Legal Representative

Shinji Kita

Haruyo Hatanaka

Teruaki Takesue

Takahisa Nakai

Yoshinori Kitagawa

Satohiro Tanaka

Kazuya Tsuzaki

Miho Yano

Tsutomu Sogo

Kazuhiko Yamamoto

Keiko Kita

Hiroshi Kawabata

Misa Ochiai

Nobushige Doisaki

Shigeru Nakamori

Shigeru Hiramoto

Yuji Shibano

Teruo Amachi

Kiyomi Furihata

Toshihiko Ashikari

Olwen M Birch

Michael Petersen

Akinori Ando

Masataka Harata

Hideko Yomo

Hirofumi Koda

Yuki Takemoto

Takehiro Matsumoto

Masashiro Funaki

Kanzo Yamashita

Masahiro Funaki

Andreas Kjener

Marie-Luise Hischier

Susanne Thöni

The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived fromincluding lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.

Method for producing oxo fatty acid and rare fatty acid

Provided is3 desaturase having high enzymatic activity even at normal temperature. A polypeptide which consists of an amino acid sequence having an identity of 80% or more with the amino acid sequence represented by SEQ ID NO: 2 and has3 desaturation activity on C20 fatty acid, and a gene thereof.

&#x3c9;3 fatty-acid desaturase and method for producing eicosapentaenoic acid

There are provided microorganisms having a property of producing a lipid containing unsaturated fatty acids as constituent fatty acids and extracellularly secreting the produced lipid encapsulated in lipid particles, methods of screening said microorganisms, as well as methods of efficiently producing a fatty acid-containing lipid using said microorganisms. Furthermore, there are provided lipid particles encapsulating a lipid containing unsaturated fatty acids, and foods, cosmetics, and animal feeds comprising said lipid particles added thereto. Artificially treated microorganisms or microorganisms collected from nature are grown on a solid medium, and microbial strains that form lipid particles at the periphery of the colonies and/or microbial strains that, when cultured in a transparent liquid medium, make the culture liquid cloudy are selected. The microorganisms obtained are cultured, lipid-containing lipid particles secreted in the culture liquid, are separated from the culture liquid, and the lipid is separated and purified.

Microorganisms that extracellularly secrete lipids and methods of producing lipid and lipid particles encapsulating lipids using said microorganisms

Microorganisms that extracellularly secrete lipid particles encapsulating lipids

An edible oil obtained by culturing a microorganism belong to the genussubgenusin a medium containing a nitrogen source derived from soybean is discussed. The oils obtained have a low 24,25-methylenecholest-5-en-3&#x3b2;-ol content.

Process for producing unsaturated fatty acid-containing oils

The present invention provides a novel acetyl-CoA carboxylase. The object of the present invention is attained by the nucleotide sequence of SEQ ID NO: 1 and the amino acid sequence of SEQ ID NO: 2 of the present invention.

Acetyl-CoA carboxylase

A highly active L-isoleucine dioxygenase fromis provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydroxy-L-isoleucine is also provided.

Method for producing 4-hydroxy-L-isoleucine

There are provided microorganisms, for example,, having a property of producing a lipid containing unsaturated fatty acids as constituent fatty acids and extracellularly secreting the produced lipid encapsulated in lipid vesicles, methods of screening said microorganisms, as well as methods of efficiently producing a fatty acid-containing lipid using said microorganisms. Furthermore, there are provided lipid vesicles encapsulating a lipid containing unsaturated fatty acids, and foods, cosmetics, and animal feeds comprising said lipid vesicles added thereto. Artificially treated microorganisms or microorganisms collected from nature are grown on a solid medium, and microbial strains that form lipid vesicles at the periphery of the colonies and/or microbial strains that, when cultured in a transparent liquid medium, make the culture liquid cloudy are selected. The microorganisms obtained are cultured, lipid-containing lipid vesicles secreted in the culture liquid, are separated from the culture liquid, and the lipid is separated and purified.

Microorganisms that extracellularly secrete lipids and methods of producing lipid and lipid vesicles encapsulating lipids using said microorganisms

Growing community of inventors

Kyoto, Japan

Sakayu Shimizu