Korea Atomic Energy Research Institute

Sajid Mushtaq

Sang Hyun Park

Dae Seong Choi

Beom Su Jang

Eui-Baek Byun

Dong-Eun Lee

Jongho Jeon

The present disclosure relates to a method for labeling a biomolecule, a fluorescent dye, or a nanoparticle compound with a radioisotope, comprising: (a) providing a cyclooctyne compound represented by the following formula (I) comprising the biomolecule, the fluorescent dye, or the nanoparticle compound which is bound to a cyclooctyne moiety of the cyclooctyne compound; and (b) reacting the cyclooctyne compound of formula (I) with a quinone compound represented by the following formula (II) to give a biomolecule, a fluorescent dye, or a nanoparticle compound labeled with the radioisotope:  

Method for labeling radioisotope, radiolabeling compounds using quinone compound and kit comprising the same for labeling radioisotope

The present disclosure relates to a method for labeling a radioisotope, a radiolabeling compound, a kit including the same, and a method for labeling a radioisotope, including: providing a diaminophenyl compound represented by Chemical Formula I below and including a biomolecule, a fluorescent dye or a nanoparticle compound bound thereto; and reacting the diaminophenyl compound and a radioisotope-labeled aldehyde compound represented by Chemical Formula II below at room temperature; and a related technology:    

Method for labeling radioisotope radiolabeling compound and kit comprising the same for labeling radioisotope

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Jeongeup-si, South Korea

Sajid Mushtaq