Bayer Aktiengesellschaft

Said Mahiout

Bernd Klinksiek

Gunther Weymans

Franz Ferdinand Rhiel

J&uuml;rgen Sdebik

Hans-J&uuml;rgen Hamann

Ricarda-Christine Nothelle

In the procedure for the production of a formulation of parenterally administrable pharmaceutical preparations, a liposome dispersion is used as a carrier for a pharmaceutical active compound. For the preparation of the liposome dispersion, an aqueous predispersion of one or more amphiphilic substances is fed to a high-pressure homogenizer in which the predispersion is pumped under a pressure from 600 bar to 900 bar through a homogenizer nozzle (,) having a diameter of 0.1 to 0.5 mm. The homogenizer nozzle has an inlet channel (,) and an outlet channel (,) and consists of a hard ceramic plate (,), in which the bore (,) is present, pressed into a steel body (,). The inlet channel (,) and the outlet channel (,) are likewise incorporated into the steel body (,).

Method and device for producing a parenteral medicament

A method of controlling concentrations in process technology operations--preferentially in thermal separation technology--using a non-linear, pressure-compensated temperature as control signal. The method can be used flexibly within a wide operating range.

Method of controlling the concentrations of a multicomponent mixture

Growing community of inventors

Bergisch Gladbach, Germany

Said Mahiout