Ngk Insulators, Inc.

Hisamitsu Pharmaceutical Company, Inc.

Chiba-prefecture

Saichi Yamada

Kazunari Yamada

Yukihisa Takeuchi

Takao Ohnishi

Toshikazu Hirota

Hiroyuki Kubo

Takeshi Goto

Akira Nakagawara

Yasuko Yoshida

Shin Ishii

Takahiro Hirata

Miki Ohira

Tsuyoshi Majima

Hideki Takeuchi

A microarray for predicting the prognosis of neuroblastoma, wherein the microarray has 25 to 45 probes related to good prognosis, which are hybridized to a gene transcript whose expression is increased in a good prognosis patient with neuroblastoma and are selected from 96 polynucleotides consisting of the nucleotide sequences of SEQ. ID NOs. 1, 5, 6, 14. 16, 17, 19, 22-24, 28, 29, 31, 37, 39, 40, 43, 44, 47-52, 54, 57-60, 62, 64, 65, 67, 68, 72-75, 77, 78, 80-82, 84, 87, 89-91, 94, 100, 103, 112, 113, 118, 120, 129, 130, 132, 136, 138, 142, 144, 145, 148, 150-153, 155, 158-160, 163-165, 169-171, 173, 174, 177, 178, 180-182, 184, 186, 187, 189, 191, 192, 194, 195, 198-200 or their partial continuous sequences or their complementary strands, and 25 to 45 probes related to poor prognosis, which are hybridized to a gene transcript whose expression is increased in a poor prognosis patient with neuroblastoma and are selected from 104 polynucleotides consisting of the nucleotide sequences of SEQ. ID NOs. 2-4, 7-13, 15, 18, 20, 21, 25-27, 30, 32-36, 38, 41, 42, 45, 46, 53, 55, 56, 61, 63, 66, 69-71, 76, 79, 83, 85, 86, 88, 92, 93, 95-99, 101, 102, 104-111, 114-117, 119, 121-128, 131, 133-135, 137, 139-141, 143, 146, 147, 149, 154, 156, 157, 161, 162, 166-168, 172, 175, 176, 179, 183, 185, 188, 190, 193, 196, 197 or their partial continuous sequences or their complementary strands.

Microarray for predicting the prognosis of neuroblastoma and method for predicting the prognosis of neuroblastoma

In a method for producing a biochip comprising a large number of spots based on captures, the spots are arranged on a base plateby supplying, onto the base plate, a plurality of types of the captures to be used to specifically react with a specimen in order to obtain information on a structure or a function of the specimen, an immobilization-reinforcing solutionis supplied onto the base plate(first supply step). Subsequently, a sample, which is obtained in a sample preparation step, is supplied onto the immobilization-reinforcing solutionhaving been supplied onto the base plateto produce the biochip thereby (second supply step).

Biochip and method for producing the same

A column for low pressure-high speed liquid chromatography, including a column body being made of a transparent or translucent plastic and having a column chamber, said column body having one end opened and the other provided with an outflow opening, a pair of upstream and downstream filters for shutting a granular filler inside said column chamber, and a head portion being made of a plastic and detachably being fitted to said one open end of the column body and having an inflow through opening communicating with interior of said column body. A column device includes the column and a method for using the column device are also disclosed for low pressure-high speed liquid chromatography.

Column and column device for low pressure-high speed liquid

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Ichinomiya, Japan

Saichi Yamada