Olix Pharmaceuticals, Inc.

Sae-Lo-Oom Lee

Dong Ki Lee

Sun Woo Hong

Tae Yeon Lee

Ji Hyun Kim

Hanna Lee

Dayeon Yu

Ji Eom

Yu Ran Na

Young-Dong Kim

In certain aspects, provided herein are RNA complexes (e.g., asymmetric RNA complexes, such as asiRNAs or cell penetrating asiRNAs) that inhibit ANGPT2 and/or PDGFB expression and are therefore useful for treating angiogenesis-associated diseases, such as cancer, AMD, and DME.

Treatment of angiogenesis-associated diseases using RNA complexes that target ANGPT2 and PDGFB

In certain aspects, provided herein are RNA complexes (e.g., asymmetric RNA complexes, such as asiRNAs or cell penetrating asiRNAs) that inhibit CTGF expression and are therefore useful for treating idiopathic pulmonary fibrosis.

Treatment of idiopathic pulmonary fibrosis using RNA complexes that target connective tissue growth factor

Growing community of inventors

Seoul, South Korea

Sae-Lo-Oom Lee