Chugai Seiyaku Kabushiki Kaisha

Sadao Tanaka

Yugo Ikeda

Minoru Shindo

Isao Matsunaga

Tamotsu Yamazaki

Yasuhiro Ohba

Shun-Ichi Hata

Kazushige Sakai

Yasuo Fujimura

Morio Kakimoto

Yasuyuki Shiraki

Novel pyrazoloindazole derivatives of the formula ##STR1## wherein R.sub.1 is a hydrogen atom, halogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxyl group or benzyloxyl group; R.sub.2 is a hydrogen atom, a halogen atom, a lower alkyl group or phenyl group (provided R.sub.1 and R.sub.2 are not hydrogen at the same time); and X.sup..crclbar. is a halide ion, a hydroxide ion, a methanesulfonate ion, a p-toluene sulfonate ion, a sulfate ion, a nitrate ion, a carbonate ion, an acetate ion, a benzoate ion or a salicylate ion, a process for preparing the derivatives, and a pharmaceutical composition containing the same are disclosed. The derivatives have good bronchodilating action for human without exhibiting substantially bad effects on the functioning of heart, and therefore, they are useful as a drug.

Pyrazoloindazole derivatives and bronchodilating composition

Benzazocine derivatives represented by the formula ##STR1## which have an excellent analgesic action and are useful for use in drugs, and a process for preparing the same are disclosed.

Benzazocine derivatives and process for preparing the same

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Tokyo, Japan

Sadao Tanaka