Other

Chondrex Inc.

Muromachi Chemical Co., Ltd.

Sadaichi Iwashita

Hiroshi Shionoya

Kuniaki Terato

Mizuo Yajima

It is believed that the abnormal absorption of endotoxin present in the gastrointestinal tract relates to the pathogenesis of autoimmune diseases such as rheumatoid arthritis. In an animal model for rheumatoid arthritis, it is observed that arthritis is improved by removing endotoxin. The present invention provides an endotoxin-adsorbent, which is capable of removing endotoxin in the gastrointestinal tract and can be administered to humans safely. By using a non-digestible and non-absorbable, and therefore, safe endotoxin-adsorbent, which has a high endotoxin-binding capacity for removing large amounts of endotoxin present in the gastrointestinal tract, it is possible to prevent and treat autoimmune diseases such as rheumatoid arthritis.

Endotoxin adsorbent for the prevention and treatment of autoimmune diseases

Endotoxin-adsorbent for the prevention and treatment of autoimmune diseases

An immunomodulator having suppressive activity on IgE antibody production is provided and contains bacterial cells, or their decomposition materials. It can be taken as a food. Bacterial cells such as Corynebacterium, Brevibacterium, Microbacterium, or bacterial cells of mutant strains of these bacteria, or decomposition products of these bacteria are used.

Immunomodulator, immunomodulator food

Growing community of inventors

Fukuoka, Japan

Sadaichi Iwashita