University of Pittsburgh

Universidad De Santiago De Chile

Upmc

Sachin Shankar Velankar

William Richard Wagner

Sang Ho Ye

Edith Tzeng

Enrique Cerda

Luka Pocivavsek

The present invention relates to substrates and composites having dynamic, reversible micron-level luminal surface deformation including texture or geometric instabilities, e.g., surface wrinkling and folding. The surface deformation and its reversal to the original surface form or to another, different surface form, is effective to reduce or prevent surface fouling and, more particularly, in certain applications, to reduce or prevent unwanted platelet adhesion and thrombus formation. The substrates and composites include a wide variety of designs and, more particularly, biomedical-related designs, such as, synthetic vascular graft or patch designs.

Tuning adhesion at contacting device interfaces: geometric tools for minimizing surface fouling

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PITTSBURGH, PA, United States of America

Sachin Shankar Velankar