Fujisawa Pharmaceutical Company, Ltd.

Toyo Seikan Kaisha, Ltd.

Saburo Obata

Kazuo Ito

Tsuguo Yabuta

Toshiaki Kamimura

This invention relates to an antimycotic composition comprising pyrrolnitrin and at least one member selected from the group consisting of lanoconazole, butenafine or a salt thereof, and an allylamine-series antimycotic agent as active ingredients, which composition has a potent antimycotic action as compared with its component drugs used each independently and is not only of great use in the treatment of dermatophytosis such as tinea, etc. and fungal infections such as candidiasis of etc. but also useful from the standpoint of alleviation of side effects and improvement in the patient's compliance.

Antifungal compositions

An applicator for an aerosol-type container having a movable nozzle projecting from its head comprises a cap and a brush attached to the cap. The cap includes, as integrally molded together, a peripheral wall fittable to the head of the container to surround the nozzle, a nozzle pushing member, and a discharge tube fittable to the nozzle for supplying a foam of detergent from the container to the brush for cleaning when the pushing member is depressed. The applicator, which has the brush, can be used and stored as attached to the container.

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Suma, Japan

Saburo Obata