Pfizer Corporation

Other

Sabeto A DiRoma

Dennis Michael Godek

Frank R Busch

Douglas J Allen

Paul Bowles

Meldrum Allen

Douglas John

A process for preparing a compounds of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, which comprises reacting a piperazine salt of the formula ##STR2## with an alkyl halide containing compound of the formula ##STR3## in water with a reagent to neutralize the hydrohalic acid and heating the mixture under conditions which are suitable to effect the coupling of said piperazine salt with said alkyl halide containing compound.

Process for preparing aryl piperazinyl-heterocyclic compounds with a

The monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydr o-2H-indole-2-one hydrochloride has advantageous stability for formulation as a neuroleptic agent.

Monohydrate of

A removable wheel and handle apparatus for use with trash receptacles such as garbage cans or the like includes a handle adapted to engage the open edge of the trash receptacle, a bracket affixed to the bottom of the receptacle and a wheel assembly adapted to removably receive an extending portion of the bracket. The handle permits easy tilting of the trash receptacle on to the wheel assembly, thereby permitting the receptacle to be readily moved from one place to another. The handle and the wheel assembly may then be removed and applied to another receptacle in a like manner.

Removable wheel and handle apparatus for trash receptacles

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Glastonbury, CT, United States of America

Sabeto A DiRoma