Other

Cloud Farm Associates, LP

Physicians Recommended Nutriceuticals, LLC

Prn Physician Recommended Nutriceuticals LLC

S Gregory Smith

Michael B Gross

Olav E Sandnes

Jeffrey Beitzel

David B Seeman

Olay E Sandnes

This invention relates to methods for treating dry eye and improving the quality of the meibum composition of inflamed or dysfunctional meibomian glands of a mammal, comprising the steps of administering a composition consisting essentially of an effective amount of omega-3 fatty acids on a daily dosage basis to the mammal having inflamed or dysfunctional meibomian glands, wherein the effective amount of omega-3 fatty acids comprises eicosapentaenoic acid (EPA) in an amount greater than 600 mg and in the re-esterified triglyceride form, and wherein the composition administered does not include any additional omega-6 fatty acids beyond the range normally found in the source material of the omega-3 fatty acids. The composition administered may facilitate an increase in levels of anti-inflammatory omega-3's in the meibum composition of the treated meibomian glands of the mammal and a decrease in the levels of inflammatory omega-6's in the meibum composition of the treated meibomian glands. The method of administering the composition of the present invention consisting essentially of omega-3 fatty acids may further comprise (1) the steps of taking a baseline measurement of tear break up time of the mammal prior to administering the composition and taking a second measurement of tear break up time of the treated mammal after administration of the composition to evaluate the improvement in tear break up time of the mammal as compared to the corresponding baseline measurement, (2) the steps of taking a baseline measurement of tear osmolarity of the mammal prior to administering the composition and taking a second measurement of tear osmolarity of the mammal after administration of the composition to evaluate the reduction of tear osmolarity of the mammal as compared to the corresponding baseline measurement and/or (3) the steps of taking a baseline measurement of the quality of tears of the mammal prior to administering the composition and taking a second measurement of the quality of tears of the mammal after administration of the composition to evaluate the improvement in the quality of tears of the mammal as compared to the corresponding baseline measurement.

Omega-3 fatty acid supplementation for use in treating dry eye

The present invention provides for a deformable, insertable device for relieving intraocular pressure comprising a body portion composed of a biocompatible porous material with pores throughout to permit drainage of fluid from the anterior chamber to the scleral tissue without collapse of the anterior chamber. The invention also includes a method for inserting the device into the eye and for using ultrasound intraoperatively to determine the position of surgical tools and devices within the sclera. The invention also includes a device excising sclera in an eye to create a chamber for insertion of the insertable device into the eye.

Eye implant devices and method and device for implanting such devices for treatment of glaucoma

The present invention provides a method of relieving intraocular pressure by inserting a drainage device into the sclera near the trabecular meshwork from a remote location. The path of insertion is made from a corneal incision and avoids contact with the conjunctiva and tenons tissue. The drainage device comprises a tube like structure and may contain a barb at one end to secure the drainage device. A delivery device may be used to insert the drainage device. The delivery device may be inserted through a corneal incision and directed to the desired area for insertion in to the sclera. The delivery device may then be activated to shoot the drainage device into the sclera to promote increased drainage of aqueous humor and reduce the build up of intraocular pressure.

This invention relates to methods for improving the quality of the meibum composition of the meibomian glands to enhance or improve the lipid layer of the tear and increase tear breakup time by way of elevating the omega-3 index in patients suffering from symptoms of dry eye, posterior blepharitis, and/or meibomian gland dysfunction. The methods comprise administering a supplementation of omega-3 fatty acids to a patient having an inflamed meibomian gland so as to facilitate an increase in the amount of omega-3's acting as an anti-inflammatory and, respectively, decrease the amount of omega-6's (arachidonic acid) acting as an inflammatory in the composition of the meibum, thereby normalizing the lipid layer of the tear and effectively reducing the associated symptoms. In certain embodiments, the supplementation of omega-3's comprises the esterified or re-esterified triglyceride form.

Methods for treating dry eye

An improved shock absorber which is capable of absorbing higher pressures created by larger deflections in the roadway and absorbing lower pressures created by smaller deflections in the roadway. The second mechanism involves the use of a first and second chamber which may expand to absorb the force of roadway defections. Additional components such as a valve, pump, tilt control unit and CPU may be used to regulate the operation of the chambers. The mechanism for absorbing lower pressures and smaller deflections may be turned on or off depending on the desires of the user. In particular, where low profile tires are used, the user may desire a stiffer suspension, and a stiffer shock absorber in a curve. In such case, it may be desirable to turn off the portion designed to absorb smaller deflections so that the car will not 'roll' when going around a curve.

Combination shock and small deflection mitigator with tire wall control in cornering

This invention relates to methods for improving changing the quality of the meibum composition of the meibomian glands to enhance or improve the lipid layer of the tear and increase tear breakup time by way of elevating the omega-3 index in patients suffering from symptoms of dry eye, posterior blepharitis, and/or meibomian gland dysfunction. The methods comprise administering a supplementation of omega-3 fatty acids to a patient having an inflamed meibomian gland so as to facilitate an increase in the amount of omega-3's acting as an anti-inflammatory and, respectively, decrease the amount of omega-6's (arachidonic acid) acting as an inflammatory in the composition of the meibum, thereby normalizing the lipid layer of the tear and effectively reducing the associated symptoms. In certain embodiments, the supplementation of omega-3's comprises the esterified or re-esterified triglyceride form.

Methods for improving the quality of the meibum composition of meibomian glands

This invention relates to methods for administering an effective amount of a dietary or nutritional supplement composition that effectively changes the quality of the meibum lipid composition of inflamed or dysfunctional meibomian glands so as to improve or increase tear break up time, reduce tear osmolarity, and elevate the omega-3 index, while reducing or eliminating the symptoms associated with dry eye or meibomianitis. The dietary or nutritional supplement composition administered to the patient suffering from inflamed or dysfunctional meibomian glands comprises an effective amount of omega-3 fatty acids.

Compositions for improving the quality of the meibum composition of inflamed or dysfunctional meibomian glands

A bushing having a variable and controllable hardness, and a method of restricting movement comprising using such bushing.

Variable response bushing

Eye glasses including a frame containing deformable lenses within the frame, the frame including means for deforming the lenses or changing the focal length of the lenses to enhance the wearer's ability to see clearly.

Deformable lens for adjustable eye glasses

An ophthalmic composition and process for treating blepharitis employing the composition of 0.5-10% of available nonionic surfactant in water to emulsify and remove lipids from the corneal surface.

Ophthalmic compositions and process of using

A golf club swing training method wherein the golfer swings a club while having a length of elastic material connected at one end to the elbow and connected at the other end at the contralateral hip of the golfer.

Golf club swing training method

A shock-absorbing, tilt-controlling system is disclosed where the shock-absorbing unit is mounted between the vehicle's frame and axle and a tilt-controlling unit is mounted remotely from, but in communication with the shock-absorbing unit.

Tilt control apparatus for vehicles

A deformable intraocular lens includes first and second plastic lens members connected to each other adjacent their peripheral edges so as to provide a cavity therebetween. The connection is realized by means of a U-shaped flange on the first member forming an inwardly facing groove that receives therein an outwardly extending flange on the second member. The U-shaped flange has a pair of angularly spaced entrance slots through which the flange on the second member is inserted. A biasing arrangement is disclosed for urging the lens members into an expanded relation. The amount of biasing force is correlated with the capability of the natural lens capsule of a human eye so that the intraocular lens can be substituted for the cataractous natural lens. Thereafter, the muscular action exerted on the natural capsule will cause my intraocular lens to flatten and thereby change the focusing thereof. Either or both of the lens members may vary in thickness to provide an additional amount of refractive correction.

Accommodating intraocular lens and method of implanting and using same

An apparatus includes a lower ring member having a frusto-conical upper surface over which the sclera of the cornea to be transplanted is placed. An upper ring member is also included. Both ring members have registrable openings of a size such that only an annular portion of the sclera outwardly of the cornea is clamped when wing nuts are tightened on a number of threaded studs pivotally attached to the lower ring member. In this way enough clamping pressure can be exerted on the sclera to prevent flow of fluid therethrough into the corneal stroma.

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Yorklyn, DE, United States of America

S Gregory Smith