Nof Corporation

Tohoku Techno Arch Co., Ltd.

Yamagata University

National University Corporation Yamagata University

Ryutaro Imamura

Eui-chul Kang

Kazushi Kinbara

Tomoyuki Ohtake

Tomoki Uruga

Hideharu Mori

Takahiro Muraoka

Adam Marcin Wawro

Eui-Chul Kang

Provided is a zwitterionic polymer that has a zwitterion that includes an effect of improving the stability of proteins. This zwitterionic polymer is a polymeric protein stabilizer that exhibits a protein stabilizing effect even at a small addition amount of addition, and at the same time has an antioxidant capability. Also provided is a method for producing this zwitterionic polymer. This problem is solved by a zwitterionic polymer containing a repeating unit represented by formula (1) and having a number-average molecular weight of 1,000 to 1,000,000. On formula (1), Rand Rare each independently selected from a hydrogen atom; linear, branched or cyclic alkyl groups having 1 to 6 carbons; aromatic groups having 6 to 20 carbons; or alkylene groups having 1 to 6 carbons and formed by linking Rto R. Rrepresents a hydrogen atom or a methyl group).

Zwitterionic polymer, method for producing same and protein stabilizer containing zwitterionic polymer

A hetero type monodispersed polyethylene glycol containing a compound represented by the following formula (1):NH&#x2014;(CHCHO)&#x2014;CHCHCOOH&#x2003;&#x2003;(1)

Hetero type monodispersed polyethylene glycol, intermediate for production of hetero type monodispersed polyethylene glycol, methods for producing same, and hetero type monodispersed polyethylene glycol conjugate

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Ibaraki, Japan

Ryutaro Imamura