Sekisui Medical Co., Ltd.

Sekisui Chemical Co., Ltd.

Other

Toyo Boseki Kabushiki Kaisha

Sekisui Kagaku Kogyo Kabushiki Kaisha

Nittobo Medical Co., Ltd.

Ryusuke Okamoto

Katsuya Togawa

Hironobu Isogawa

Hideo Anraku

Masatoshi Niunoya

Tomonori Inoue

Kuniya Komai

Yuuji Setoguchi

Masahiro Nakaizumi

Kana Hayashi

Hironobu c/o Sekisui Chemical Co Ltd Isogawa

There is provided a composition for separating blood serum or blood plasma that can inhibit bubbling during sterilization, and can inhibit the occurrence of phase separation during storage. The composition for separating blood serum or blood plasma according to the present invention comprises a (meth)acrylic acid ester-based polymer, a silica fine powder, and a silicone oil, wherein the (meth)acrylic acid ester-based polymer has fluidity at room temperature, and has a weight average molecular weight of 15000 or more and 100000 or less.

Composition for separating blood serum or blood plasma, blood collection container, and method for separating blood serum or blood plasma

To provide a device for concentration and separation of circulating tumor cells, capable of recovering circulating tumor cells in a blood-derived specimen simply, at a high recovery rate, and with low invasion of the tumor cells. A device for concentration and separation of circulating tumor cells present in a blood-derived specimen, in which a cell separating agent with thixotropic property having a specific gravity ranging from 1.050 to 1.080 and enabling the separation of tumor cells and blood cells other than the tumor cells by a centrifugal operation is housed in a bottomed tube-shaped container closed at one end and opened at the other end.

Device for concentration and separation of circulating tumor cells, and method for concentration and separation of circulating tumor cells

There is provided a serum- or plasma-separating composition less likely to cause separation between a liquid organic compound and a thixotropy imparting component and capable of maintaining a homogeneous blended state for a prolonged period. The serum- or plasma-separating composition comprises a liquid organic compound, a thixotropy imparting component, and a thermoplastic elastomer.

Serum- or plasma-separating composition, blood-test container, and method of stabilizing serum- or plasma-separating composition

There is provided a serum- or plasma-separating composition capable of maintaining stable blood separation performance over a prolonged period even if subjected to a sterilization step during production or to prolonged storage. The serum- or plasma-separating composition comprises a resin composition having fluidity at normal temperature, a silica fine powder, and an amide-based compound represented by the following formula (1): wherein Ris an alkyl group having 1 to 4 carbon atoms; and Rand Rare independently a hydrogen atom or a linear or branched alkyl group having 1 to 8 carbon atoms.

Composition for serum or plasma separation, and container for blood collection

A plug that allows the plug body to be easily and reliably pierced through by a hollow bodily fluid collection needle, makes the bodily fluid collection needle difficult to draw back out of the plug body owing to a resilience of a sheath after the start of bodily fluid collection, and enables easy and reliable collection of the bodily fluid. The plugis a plug for closing an opening end of a bodily fluid-collecting containerwhich is to be inserted into a tubular holder, and includes: a plug bodyto be fixed to the opening end of the bodily fluid-collecting container; and a cover membersheathed on the plug bodyto cover an outer surface of the plug body, wherein the cover memberincludes a side partcovering the outer surface of the plug body, and an outer surface of the side partis provided with a protrusionwhich protrudes radially outward of the side partof the cover memberto come into contact with and give frictional resistance to an inner wall of the holderupon insertion into the holder

Plug and bodily fluid-collecting instrument set

Provided is a plug that enables reliable and easy removal of a plug body together with a cover member from a tubular container without increasing an outwardly-bulging flange portion of a grip part of the plug body and is superior in productivity. A plugfor closing an open end of an open-ended tubular container. A cover memberis fitted on a plug bodyincluding a press-fit partand a grip part. An engagement portionis extended from a head plateof the cover memberinto a recessin the upper surface of the plug bodyto face an inside wallsurrounding the recess. When an external force is applied to incline the head platewith respect to the upper surface of the plug body, the engagement portionis engaged to the inside wall

Plug

Cap for a blood collection tube

Blood separation material which separates blood collected in a blood-sampling container, into blood cells and plasma or serum within a short period of time. An apparatus for separating blood with the blood separation material. An instrument for separating blood having a first hollow needle extending toward one end, a second hollow needle extending toward the other end, a tubular container with an inner space in which the blood flows, and a blood separation material. A container with a first channel for supplying blood into an inner space through which blood flows from the needlepoint of the first hollow needle into the inner space, a second channel for blood to flow out from the inner space toward the needlepoint of the second hollow needle, and a third channel which allows air to flow from the outer space toward the needlepoint of the first hollow needle.

Instrument for separating blood and apparatus for separating blood

The present invention provides a blood collection container capable of allowing blood to coagulate in a short time and preventing blood from coagulating with bubbles contained therein and thus preventing formation of bubbly clots when used to collect blood therein. A blood collection containerstores a blood coagulation promoting agentfor promoting blood coagulation and an antifoaming agent, which is a polyoxyalkylene or a derivative thereof. The amount of the antifoaming agentis 2.0&#xd7;10to 0.2 mg per mL of blood to be collected in the blood collection container

Blood collection container

Provided is a blood separating agent that can form an excellent partition wall in an intermediate layer between clot and serum or between blood cell components and plasma even under low-temperature centrifugation conditions, is less likely to form crevices in the partition wall, is less likely to have any effect on test values, and offers stable performance even after long-term storage. The blood separating agent contains: a polymer for the blood separating agent which is composed of a (meth)acrylic acid ester-based polymer and has a viscosity of 10 to 200 Pa&#xb7;s at 25&#xb0; C. and a ratio of viscosity at 15&#xb0; C. to viscosity at 25&#xb0; C. of below 4.6; an inorganic powder; and a polyalkylene glycol having a number average molecular weight of 700 or more, wherein the polyalkylene glycol is mixed at a concentration of 5% by weight or less of the total weight of the blood separating agent.

Blood separating agent and blood collection container

The present invention provides a blood coagulation promoter capable of exerting both excellent blood coagulation promoting ability and excellent blood clot detaching ability; and a blood collection tube accommodating the blood coagulation promoter. The present invention provides a blood coagulation promoter which includes a hardly water soluble polyoxyalkylene derivative; a partially saponificated polyvinyl alcohol; at least one substance selected from the group consisting of adsorptive inorganic substances and hydrolases capable of hydrolyzing a bond between Arg and an arbitrary amino acid reside and/or a bond between Lys and an arbitrary amino acid residue in a peptide chain; a polyvinylpyrrolidone; and preferably a water-soluble silicone oil, and a blood collection tube in which the blood coagulation promoter is accommodated in a tubular vessel having a bottom.

Blood coagulation promoter and blood collection tube comprising a polyoxyalkylene glycerin derivative

A Plasma or serum separation membrane that enables omitting centrifugal separation, is free from hemolysis attributed to destruction of red blood cells and realizes easy and rapid separation of plasma or serum from blood; and a filter apparatus including the plasma or serum separation membrane. In particular, a plasma or serum separation membrane being a membrane for separation of plasma or serum from blood and having a void ratio of 30% or below; and a filter apparatus comprising a filter member capable of attaining movement of plasma swifter than movement of blood cells and a plasma or serum separation membrane connected in series with a rear side of the filter member.

Growing community of inventors

Shunan, Japan

Ryusuke Okamoto