Ajinomoto Co., Ltd.

Ryotaro Nakaya

Daisuke Takahashi

Keiichi Yokoyama

Satoshi Katayama

Takayoshi Torii

Kunihiro Hirai

Fumi Shozui

Takashi Ineyama

Polyester compounds obtained by reaction of a compound represented by formula (1): (defined herein) with a compound represented by formula (2): (defined herein) exhibit high thermal resistance.

Polyester compound

The present invention provides a protected nucleotide for elongation, which can be purified efficiently and in a high yield by a liquid-liquid extraction operation, and can achieve an oligonucleotide production method by a phosphoramidite method. It has been found that the above-mentioned problem can be solved by a particular oligonucleotide comprising a protected base and/or particular oligonucleotide protected by a branched chain-containing aromatic group at 3'-position.

Oligonucleotide with protected base

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Kawasaki, Japan

Ryotaro Nakaya