Fuji Photo Film Company, Limited

Fujifilm Corporation

Fuji Immunopharmaceuticals Corp.

Ryoichi Nemori

Yasuo Mukunoki

Hiroshi Kitaguchi

Hiroshi Kawasaki

Mitsunori Ono

Koki Nakamura

Stephen D Gillies

Hideaki Naruse

Ichizo Toya

Shigeki Yokoyama

Hiroki Sasaki

Hideo Ikeda

Kin-Ming Lo

Yoshihisa Tsukada

Junji Nishigaki

Yumiko Wada

Yaming Wu

Kouki Nakamura

Takayasu Yasuda

Yasunori Okada

Yutaka Tamura

Yuuichi Okamoto

Tetsuo Takeuchi

Masayoshi Yamamoto

Hiroshi Kaise

Mikihiro Kusama

Yumiko Jimbo

It is disclosed a polymerizable composition for producing an optical member for 850 nm wavelength comprising: a polymerizable monomer composition and a compound, having a different refractive index from that of the polymerizable monomer composition, whose structure has a benzene ring substituted by a substituent having a Hammett value of not greater than 0.04 or by plural substituents having an average value of Hammett values thereof of not greater than 0.04. It is also disclosed a polymerizable composition for producing an optical member comprising a polymerizable monomer composition comprising at least one selected from the group consisting of Calicyclic (meth)acrylates and a compound, having a different refractive index from that of the polymerizable monomer composition and having a solubility parameter of not greater than 10.9, whose structure has a benzene ring substituted by the substituent or the substituents defined above.

Optical members and compositions for producing them

A thin membrane for measuring protease activity, which is formed on a support and, which comprises one or more kinds of substances selected from the group consisting of a transferrin derivative and an albumin derivative and is crosslinked and/or substantially water-insoluble. The membrane enables selective measurement of protease activity of a particular class of protease such as matrix metalloproteinase 7.

Thin membrane for measuring protease activity

A method for measuring a thiol group-containing compound, which comprises the steps of (1) contacting a sample containing a thiol group-containing compound with a thin membrane comprising a microparticle of a substance selected from the group consisting of a metal and a metal compound and comprising a hydrophilic binder; and (2) detecting a color change on the thin membrane resulting from interaction of the thiol group-containing compound and the microparticle, and a thin membrane used for said method. A thiol group containing compound such as an alkylmercaptan or a protein containing thiol groups can be conveniently and accurately measured.

Thin membrane for detecting thiol-containing compounds

Method for measuring protease activity

A method for judging effectiveness of a drug having protease inhibitory activity, which comprises the steps of: (1) bringing a biosample isolated or collected from a patient with a disease in which participation of a protease is suspected into contact with a thin membrane containing a protease substrate and formed on a surface of a support; (2) detecting a trace of digestion formed on the thin membrane by action of a protease; and (3) judging that a drug having protease inhibitory activity is effective for the patient when a trace of digestion is formed on the thin membrane. The method enables accurate judgment as to whether or not a drug having protease inhibitory activity is effective for a patient with a disease in which participation of a protease is suspected such as rheumatoid arthritis and cancer before administration of the drug.

Method for judging effectiveness of drug having protease inhibitory activity

A method for inhibiting retroviral infection in a subject comprising administering to said subject a therapeutically effective amount of a naphthalenesulfonic acid compound or a pharmaceutically acceptable salt thereof, as herein defined.

Method for inhibiting retroviral infection by administering a

A peptide derivative amphiphatic compound or N-terminal salt thereof represented by formula (I): ##STR1## wherein R.sup.1 and R.sup.2 each represents a straight-chain or branched alkyl or acyl group having 8 to 24 carbon atoms optionally having a substituent or an unsaturated group; X represents --O--or --NH--; R.sup.3n and R.sup.3(n+1) each represents an .alpha.--amino acid side chain; n is an integer of from 0 to 5; the compound may be a racemic compound or an optically active compound when the compound has an asymmetric carbon atom; and the N-terminal salt of the compound optionally forms with an acid component; an intermediate thereof, a liposome comprising said peptide derivative amphiphatic compound and a film consisting of a monolayer or multilayers comprising the peptide derivative amphiphatic compound are disclosed.

Peptide derivative amphiphatic compound, intermediate thereof and

A silver halide photographic material which comprises a support having thereon at least one hydrophilic colloid layer, wherein the hydrophilic colloid layer comprises (a) a binder comprising a dextran having a molecular weight of at least 100,000 and (b) an ionic polymer.

Silver halide photographic material

A method for activating a membrane comprising cellulose as a main component, by reacting the membrane with a compound of the formula Cl-SO.sub.2 -R or Cl-CO-R.sub.1 where R is an optionally substituted alkyl or phenyl group and R.sub.1 is a releasing group, an activated membrane obtained by the method, a method of fixing a physiologically active substance on the activated membrane and a physiologically active substance-fixed membrane obtained by the method. A physiologically active substance can be fixed on the activated membrane by stable chemical bond between the substance and the membrane while maintaining the physiological activity of the substance.

Method for activating cellulosic membrane, activated cellulosic

A thiocyanate-containing silver halide emulsion, characterized in that a disc tablet of 2.5 mm in diameter formed of 10 mg of silver halide contained in the silver halide emulsion shows an absorbance of 0.015 or higher or thiocyanate ion at 2052 cm.sup.-1, measured by IR spectroscopy. The emulsion is high in sensitivity, small in loss of photographic sensitivity caused by pressure and small in fluctuations in results of photographic processings.

Silver halide emulsion containing a thiocyanate compound having specific

A silver halide photographic light-sensitive material is described, comprising a support having provided thereon at least one silver halide emulsion layer, wherein there is at least one hydrophilic colloidal layer containing at least one nonionic surface active agent and at least one anionic surface active agent having a polyoxyethylene group therein.

Silver halide photographic light-sensitive material

A silver halide photographic material is disclosed comprising a support having thereon at least one layer containing a nonionic surface active agent having a polyoxyethylene group and a fluorine-containing compound, wherein the element composition of the surface of said layer has a ratio of F.sub.ls peak intensity/C.sub.ls peak intensity in the range of 0.3 to 2.0 when measured by an X-ray photoelectron spectrometry.

Growing community of inventors

Kanagawa, Japan

Ryoichi Nemori