Tokai National Higher Education and Research System

Yamasa Corporation

Ryohei Kajino

Yoshihito Ueno

Yusuke Maeda

A nucleoside that is more practical for RNA pharmaceuticals and other applications and use thereof is represented by formula (1) or (2) below, or a salt thereof: (In formula (1), Rrepresents a hydrogen atom, a hydroxyl group, a hydroxyl group in which a hydrogen atom is substituted by an alkyl group or alkenyl group, or a protected group, and in formula (2), X represents a halogen atom. In formula (1) and formula (2), Rand Rmay be the same or different, and each represents a hydrogen atom etc., Rrepresents NHR(in which Rrepresents a hydrogen atom etc., and B represent represents any of a purine-9-yl group, 2-oxo-pyrimidin-1-yl group, substituted purine-9-yl group or substituted 2-oxo-pyrimidin-1-yl group).

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Gifu, Japan

Ryohei Kajino