The University of Tokyo

Yuasa System Co., Ltd.

Ryo Taguchi

Hiroyuki Arai

Yoshihito Ota

Hisao Sasaki

Yasuhisa Okazaki

Makoto Arita

Atsushi Shishido

Yousuke Isobe

Norihisa Akamatsu

Provide is a deformation testing apparatus in which a sign of breakage of a specimen under a deformation test can be detected before an actual breakage. The deformation testing apparatus carrying out a plurality of deformation cycles includes an image capturing means; reference data storing means storing the reference data showing the deformation state calculated based on the reference image data shot by the image capturing means; reference cycle number deformation data calculating means to calculate the reference data; detection cycle number deformation data calculating means to calculate detection cycle number deformation data showing the deformation state based on the detection image data shot at the detection cycle number being larger than the reference cycle number; and change detection means to detect that the deformation caused in the specimen is changed based on the reference cycle number deformation data and the detection cycle number deformation data.

Deformation testing apparatus

An object of the present invention is to provide a compound having a novel structure for overcoming the defects of conventional steroid agents and NSAIDs. It is found that the particular dihydroxy bodies of eicosapentaenoic acid and docosahexaenoic acid, which have not conventionally been known (11,18-dihydroxy eicosapentaenoic acid (11,18-diHEPE), 17,18-dihydroxy eicosapentaenoic acid (17,18-diHEPE) etc.), have activity of inhibiting neutrophil, thereby solving the object. The present invention unexpectedly remarkably inhibits infiltration into a tissue of, and activation of neutrophil found out at acute inflammation. The compound of the present invention is a compound which has not conventionally been known. Therefore, utility as a new therapeutic is provided.

Anti-inflammatory compounds

Growing community of inventors

Tokyo, Japan

Ryo Taguchi