Teijin Limited

Ryo Sogawa

Kazuya Takenouchi

Kenji Manabe

Seiichi Ishizuka

Qingzhi Gao

Yasuhiro Takano

Compounds expressed by the following general formula (1),[wherein, Rand Rare each independently a hydrogen atom or a protecting group for a hydroxyl group; Z is one out of the following formulae (1-1), (1-2), (1-3), (1-4) and (1-5)].The compounds can be used as active ingredients of treating agents for inflammatory respiratory diseases, malignant tumors, rheumatoid arthritis, osteoporosis, diabetes mellitus, hypertension, alopecia, acne, psoriasis, dermatitis, hypercalcemia, hypoparathyroidism and metabolic disorder of cartilage.

Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same

Compounds expressed by the following general formula (1),[wherein, Rand Rare each independently a hydrogen atom or a protecting group for a hydroxyl group; Z is one out of the following formulae (1-1) to (1-5)].The compounds can be used as active ingredients of treating agents for inflammatory respiratory diseases, malignant tumors, rheumatoid arthritis, osteoporosis, diabetes mellitus, hypertension, alopecia, acne, psoriasis, dermatitis, hypercalcemia, hypoparathyroidism and metabolic disorder of cartilage.

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Tokyo, Japan

Ryo Sogawa