Nitto-denko Corporation

Biomedical Research Group Inc.

Macrophi Inc.

Ryo Hashino

Gen-Ichiro Soma

Jun Harima

Akira Numata

Chie Kohchi

Masakatsu Konno

Junichi Sekiya

Hidetoshi Kuroda

Tsuyoshi Kasahara

Jun Ishikura

Yu Tachikawa

Satoshi Ameyama

Raito Funayama

Kyohei Matsushita

Hiroyuki Inagawa

Wenjing Li

An adhesive patch containing an adhesive patch main part containing a support and an adhesive layer laminated on the support, wherein the adhesive patch main part has a peripheral part, a central part, and an intermediate part between the peripheral part and the central part, the intermediate part of the adhesive patch main part has a thickness greater than that of the central part of the adhesive patch main part, and the central part of the adhesive patch main part has a thickness greater than that of the peripheral part of the adhesive patch main part, and a production method thereof.

Adhesive patch

The invention provides a process for producing an adhesive patch, which includes a step of preparing a pressure-sensitive adhesive sheet including a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner disposed on the pressure-sensitive adhesive layer; and a step of punching an adhesive patch including a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner disposed on the pressure-sensitive adhesive layer out of the pressure-sensitive adhesive sheet with a protrudent push cutter blade, in which, at at least an edge part of the protrudent push cutter blade, a cross-sectional shape of the protrudent push cutter blade, which is in a direction perpendicular to the direction in which the protrudent push cutter blade extends, has an angle a and an angle b, in which the angle a is larger than the angle b. The angle a and angle b in the sectional shape have the meanings described in the specification.

Process for producing adhesive patch

The patch according to an embodiment of the present invention includes: a support; and a pressure-sensitive adhesive layer on at least one surface of the support, wherein: the pressure-sensitive adhesive layer contains an acrylic copolymer obtained by copolymerizing monomer components containing (a) at least one kind of a monomer of a (meth)acrylic acid alkyl ester and (b) at least one kind of a monomer of an N-hydroxyalkyl(meth)acrylamide; a content of the (meth)acrylic acid alkyl ester monomer (a) with respect to a total amount of the monomer components is 50 wt % to 90 wt % and a content of the N-hydroxyalkyl(meth)acrylamide monomer (b) with respect to the total amount is 1 wt % to 20 wt %; and the monomer components are substantially free of a monomer having a carboxyl group.

Transdermal patch having a pressure-sensitive adhesive comprising (meth)acrylic acid alkyl ester, N-hydroxyalkyl(meth)acrylamide, and vinyl monomers

The present invention provides an adhesive patch comprising a support, an adhesive layer on at least one surface of the support, and a release liner on a surface of the adhesive layer opposite from the support, wherein (a) the lateral end of the adhesive layer is exposed, (b) in at least one lateral end, the lateral end of the adhesive layer is located toward the central part side of the adhesive patch from the lateral end of the support, and (c) when placed horizontally with the release liner facing down, a distance A between the upper end of the support and the lower end of the release liner at said lateral end of the adhesive patch is greater than a thickness B of the central part of the adhesive patch.

Adhesive patch and adhesive preparation

An adhesive patch has a support and an adhesive layer formed on at least one surface of the support. The adhesive patch has a peripheral part and a central part. The adhesive layer has voids localized in the peripheral part, with the adhesive layer in the central part being substantially free of voids. The peripheral part preferably contains voids at 2.0-100 voids/mmon average. Since time-course changes of adhesive layer components such as additives are reduced, the adhesive patch is highly resistant to detachment from the skin, the components do not easily protrude from the edge of the adhesive patch during preservation in a package, adhesion to the inner surface of the package is suppressed, the adhesive patch can be easily removed from the package and edge lifting by cold flow is suppressed during adhesion to the skin.

Growing community of inventors

Ibaraki, Japan

Ryo Hashino