Terumo Bct Biotechnologies, LLC

Rylan A Summit

Dennis A Bridges

Kestas P Parakininkas

Nathaniel T Johnson

Margaret V Kwiat

Alexander Du Nguyen

Dennis J Hlavinka

Kirk L Weimer

Michael Lawrence Glover

Provided is a gas fill fixture for use in lyophilization, a related system and method. The gas fill fixture includes a chassis, fill indicator and a lid, such that the chassis and lid together form a cavity for receiving a flexible lyophilization container. The system includes a lyophilization container, a lyophilizer and a gas fill fixture incorporating a chassis, a fill indicator and a lid. The method includes process steps for using the system to lyophilize a fluid.

Lyophilization container fill fixture, system and method of use

Provided is a loading tray assembly for housing a lyophilization container and a related system and method. The loading tray assembly includes a chassis including a contact void configured to facilitate direct contact between the attached lyophilization container and a lyophilizer shelf. The method includes securing a multi-part lyophilization container including a peelable seal on a lyophilization loading tray assembly, inputting a liquid into a non-breathable section of the lyophilization container, loading the tray assembly into a lyophilizer, freezing the liquid, applying heat energy and a vacuum, the vacuum causing an opening of the peelable seal and occluding the lyophilization container to isolate the frozen liquid.

Lyophilization loading tray assembly and system

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Denver, CO, United States of America

Rylan A Summit