University of Kentucky Research Foundation

Teradyne, Inc.

Ryan Vallance

Bruce Lanier Walcott

Daniel Wermeling

John Alan Main

James E Lumpp

Aravind Balasubramaniam

Sepehr Kiani

An apparatus and method for the self-administration of a plurality of doses of an intranasal liquid pharmaceutical composition, including opioid analgesics, that includes a drug delivery device containing a plurality of sealed vials, each vial containing a predetermined volume of the pharmaceutical composition, a pump assembly for conveying the liquid pharmaceutical composition from the interior of the vial and discharging it as a nasal spray in response to manual activation by the patient, and programmable means for sequentially advancing a vial to the ready position after passage of a prescribed time interval following the last activation of the delivery device.

Programmable multi-dose intranasal drug delivery device

A ferrule assembly, in a preferred embodiment, having a first ferrule, a second ferrule, and at least two alignment members to align the first and second ferrules during mating is provided. The first ferrule, the second ferrule and the alignment members interact at the mating interface of the first and second ferrules to provide three constraint lines. In one embodiment, the first ferrule has a body with at least one channel for receiving at least one optical fiber. The first ferrule body includes a first surface portion for retaining a first alignment member and a second surface portion for retaining a second alignment member, the first and second surface portions being V-shaped. The second ferrule has a body with at least one channel for receiving at least one optical fiber. The second ferrule body includes a first surface portion for retaining the first alignment member and a second surface portion for retaining the second alignment member, the first surface portion being V-shaped and the second surface portion being flat.

Optical connector ferrule designed to minimize manufacturing imperfections and mating misalignments by incorporating exact constraint principles

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Lexington, KY, United States of America

Ryan Vallance