Wisconsin Alumni Research Foundation

Purdue Research Foundation

Ryan Tyler Hilger

Lloyd M Smith

Joshua J Coon

Mark Andrew Scalf

Michael Robert Shortreed

Jason Dale Russell

Daniel T Ladror

Hilkka I Kenttamaa

James Robert Zimmerman

Ravikiran Yerabolu

John Kong

Tiffany Prentice

Chunfen Jin

A multichannel inlet system for a mass spectrometer includes a plurality of valve assemblies coupled to a manifold, and a pulsed valve driver. The manifold is configured to be connected in fluid connection with an ion trap of the mass spectrometer. Each valve assembly includes a valve and an injection port operably coupled to receive the reagent. The valve has an actuated state in which the valve provides fluid communication between the injection port and the manifold, and an unactuated state in which the valve substantially prevents fluid communication between the injection port and the manifold. The pulsed valve driver is operably connected to receive a pulse signal sequence from a processor, and is configured to generate pulsed valve drive signals for one or more of the valves based on the pulse signal sequence to cause a corresponding one of the valves to be in the actuated state.

Multi-channel pulsed valve inlet system and method

Heating devices, systems, and methods of making and using a heating device. Such a heating device includes a tubular body having a passage therethrough, at least an inner layer surrounding the passage, and an outer layer surrounding the inner layer. The inner layer is electrically resistive and the outer layer is electrically insulating, and the passage is sized and configured to receive therethrough a tubing. The heating device further includes electrical contacts located at oppositely-disposed ends of the tubular body. The contacts are configured to functionally couple with a power source to provide an electrical current to the inner layer, such that applying an electrical current to the inner layer increases the temperature of the inner layer.

Devices for heating small-diameter tubing and methods of making and using

An integrated mass spectrometer electrospray emitter and fluorescence detector allows improved volumetric measurements of separate components from a liquid chromatography column by improving correlation between the readings of these instruments and reducing dead volume and sample size requirements.

Integrated electrospray ionization emitter and detection cell for parallel measurements by fluorescence and mass spectrometry

Growing community of inventors

Lafayette, IN, United States of America

Ryan Tyler Hilger