Geneweave Biosciences, Inc.

Tdk Corporation

Nanosphere, Inc.

Roche Molecular Systems, Inc.

Luminex Corporation

Lucira Health, Inc.

Dots Technology Corp.

Ryan Griswold

Bruce J Richardson

Shaunak Roy

Werner Frei

Kenneth G Olson

Diego Ariel Rey

Victor H Yee

Vibhu Vivek

John Sze

Tom Westberg

Chris Lewis

Soni Shukla

Nikol De Forest

Doran Donnelly

Leonardo Maestri Teixeira

Rick V Stellmacher

Lance Page

Gregory J Kintz

Debkishore Mitra

Frank B Myers, Iii

John Robert Waldeisen

Ivan Krastev Dimov

Adam Young

Adi Gilboa-Geffen

Paul Fleming

Patrick Murphy

Joshua Glenn Anthony

Damian S Matthews

Brett Gorham

Wei Hsuan Ho

Sensor modules mountable on a wheel are described. A sensor module mountable adjacent to a rim of a wheel includes a first set of one or more piezoelectric sensors; and a first elastic support with the first set of one or more piezoelectric sensors coupled thereon so that the first set of one or more piezoelectric sensors are spaced apart from the rim of the wheel. A wheel that includes a rim and the sensor module is also disclosed. A method includes receiving a force on a tire mounted on a rim of a wheel. The tire is in contact with an elastic support with one or more piezoelectric sensors coupled thereon so that the force causes strain in the elastic support and the one or more piezoelectrical sensors. The method also includes, in response to receiving the force, generating electrical signals from the one or more piezoelectric sensors.

Devices and methods for overloading protection of piezoelectric material mounted on wheels

Systems and methods for an energy harvester coupled to a rotatable component of a vehicle are disclosed. In some embodiments, an energy harvester system includes at least one energy harvesting component configured to be attached to a wheel of a vehicle, wherein the at least one energy harvesting component includes a piezoelectric component configured to be directly attached to a staging surface of the wheel, wherein the piezoelectric component is configured to deform in response to a mechanical strain imparted on the piezoelectric component as the wheel rotates and generate an electric signal.

Smart wheel energy harvester

Piezoelectric devices mountable on a rigid mechanical structure are described. A piezoelectric device includes one or more piezoelectric elements and one or more supporting structures. A respective supporting structure of the one or more supporting structures has a flat or non-flat surface and is mechanically coupled with a piezoelectric element of the one or more piezoelectric elements so that a mechanical force on the one or more supporting structures is converted into an electrical signal by the one or more piezoelectric elements. A piezoelectric device system including two or more piezoelectric devices and a method for generating electrical signals are also described.

Piezoelectric energy harvesters and sensors based on strain in mechanical structures

Systems and methods for an energy harvester proximate to a rotatable component of a vehicle's wheel are disclosed. In some embodiments, an energy harvester system includes: a plurality of energy harvesting components configured to be coupled to a rotatable component in a ring formation along a circumference of the rotatable component, wherein each of the plurality of energy harvesting components includes: a substrate configured to be attached to a surface of the rotatable component; a piezoelectric component coupled to a surface of the substrate, wherein the piezoelectric component is configured to deform in response to a mechanical strain imparted on the piezoelectric component as the rotatable component rotates and generate an electric signal; and an interconnect coupled to the piezoelectric components and configured to conduct the electric signal from the piezoelectric components to a device coupled to the rotatable component.

Systems and methods for an energy harvester proximate to a rotatable component of a vehicle's wheel are disclosed. In some embodiments, an energy harvester system includes: a substrate having a first surface configured to contact and interface with a surface of a wheel, and a second surface opposite the first surface; a piezoelectric component configured to produce energy in response to mechanical strain imparted on the piezoelectric component, wherein the piezoelectric component is configured to deform while experiencing the mechanical strain so as to contact at least a portion of the second surface.

The present invention is drawn to devices and systems for allergen detection in a sample. The allergen detection system includes a sampler, a disposable analysis cartridge and a detection device with an optimized optical system. In some embodiments, the allergen detection utilizes aptamer nucleic acid molecules as detection agents. In some embodiments, the nucleic acids are conjugated to magnetic beads or solid surfaces such as glasses, microwells and microchips.

Systems for allergen detection

Energy harvesting device

An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to a reaction chamber. A delivery portion of the housing defines a delivery path between the reagent volume and the reaction chamber when the housing is coupled to the reaction chamber. The delivery path includes a protrusion such that the delivery path has a discontinuous inner surface. The actuator can be moved to convey a reagent from the reagent container into the reaction chamber via the delivery path.

Reagent cartridge for detection of cells

Disclosed are cartridges and modules that may be utilized in diagnostic systems and methods. The cartridge includes a flexible seal that caps the cartridge. The flexible seal has an opening for a pipette tip, and the flexible seal is configured to create a sealed environment when a pipette tip is positioned in the opening of the flexible seal and when the pipette tip is moved in the X-axis, Y-axis, and Z-axis.

Diagnostic cartridges having flexible seals

Devices and methods for preparing and delivering biological assay samples are provided herein. Components of such devices include a sample receiving module within which a biological assay sample can be prepared and a cap, which when operatively coupled with the sample receiving module, pressurizes the module. These devices can be employed for subsequently delivering a biological assay sample.

Devices and methods for biological assay sample preparation and delivery

Systems and methods for detecting and/or identifying target cells (e.g., bacteria) using engineered transduction particles are described herein. In some embodiments, a method includes mixing a quantity of transduction particles within a sample. The transduction particles are associated with a target cell. The transduction particles are non-replicative, and are engineered to include a nucleic acid molecule formulated to cause the target cell to produce a series of reporter molecules. The sample and the transduction particles are maintained to express the series of the reporter molecules when target cell is present in the sample. A signal associated with a quantity of the reporter molecules is received. In some embodiments, a magnitude of the signal is independent from a quantity of the transduction particle above a predetermined quantity.

Systems and methods for detection of cells using engineered transduction particles

An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to a reaction chamber. The housing includes a puncturer that defines a transfer pathway in fluid communication with the reagent volume. A delivery portion of the housing defines a delivery pathway between the transfer pathway and the reaction chamber when the housing is coupled to the reaction chamber. The actuator has a plunger portion disposed within the reagent volume. An engagement portion of the actuator can be manipulated to move the plunger portion within the reagent volume to deform the reagent container. The puncturer can pierce a frangible portion of the reagent container to convey a reagent from the reagent container into the reaction chamber via the transfer pathway and/or the delivery pathway.

Reagent cartridge and methods for detection of cells

Growing community of inventors

Los Gatos, CA, United States of America

Ryan Griswold