Avent, Inc.

Avent Investment, LLC

Ryan Caldwell

Eric Anthony Schepis

Phillip A Schorr

Amol Soin

David M Page

Shyamy R Sastry

Natalia Alexeeva

Leah M Roldan

Shyamant Ramana Sastry

Jalpa Shah

Wanzhan Liu

Lee C Burnes

Gleb Klimovitch

Todd Hanson

Chris Zobkiw

Leah Roldan

Daniel Oster

Anthony Boyle

Shyamant R Sastry

The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.

Device and method to selectively and reversibly modulate a nervous system structure to inhibit pain

The present invention is directed to a system and method for adaptive multivariate control for performing a radiofrequency (RF) ablation procedure with an energy delivery device. The system includes an energy source for delivering energy to a patient's body; one or more energy delivery devices; two or more sensors for measuring at least two factors related to an ablation procedure, respectively; and at least one processor. The method includes steps of: measuring at least two factors related to an ablation procedure; determining a first operating threshold based, at least in part, on a first factor; controlling an energy delivery device based on the first operating threshold to create a lesion at the target site within the patient; determining a second operating threshold based, at least in part, on a second factor; switching control of the energy delivery device from the first factor to the second factor; and controlling the energy delivery device based on the second operating threshold to create a lesion at the target site within the patient. The present invention is also directed to a RF probe configured to be used with the adaptive multivariate control system and method to perform RF ablation procedures.

Radiofrequency probe, system, and method for adaptive multivariate control of an ablation procedure

The present disclosure is directed to a portable system and method for modulating targeted neural and non-neural tissue of a nervous system to block nerve conduction for the treatment of pain. A high-efficiency portable electrical stimulation system is provided that allows a user to carry the system and move around freely while continuously receiving therapy. The electronic control system is configured to deliver high-frequency electrical stimulation at a therapeutic level, for an intended duration (e.g., up to 24 hours or more) at a manageable and/or comfortable weight for a person, to the target nerve.

Portable electrical stimulation system and method

The exemplified systems and methods facilitate a nerve conduction block at a target nerve using electrical stimulation applied from one or more electrodes located on a percutaneous lead that are placed in parallel, or substantially in parallel, and without direct contact, to a long axis of the peripheral nerve over an overlapping nerve region of greater than about 3 millimeters. The exemplified system and method can be further configured to block nerve condition without eliciting onset activity and co-excitation of non-targeted structures. The exemplified method and system can be performed using conventional percutaneous leads, though an improved percutaneous lead design is disclosed herein. In an aspect, an introducer is disclosed that facilitates accurate and consistent insertion of the percutaneous lead to the specified or intended position relative to the target nerve. In another aspect, a treatment kit comprising the various system components to treat pain is disclosed.

Percutaneous lead placement assembly

Treatment kit to percutaneously block painful sensations hosted by a peripheral nerve

System and method to percutaneously block painful sensations

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Alpharetta, GA, United States of America

Ryan Caldwell