Cedars-sinai Medical Center

Capricor, Inc.

Russell Thomas Rogers

Eduardo Marban

Luis Rodriguez-Borlado

Mark Amin Aminzadeh

Jennifer Moseley

Saravana Kanagavelu

Christopher Stewart Sakoda

A grip strap magnetic mounting device for supporting objects such as water bottles within a strap. The device is configured to magnetically connect to various metallic surfaces, including surfaces of exercise equipment. The strap is connected to a magnet. The strap includes a grip portion for preventing an object from slipping out of the strap. The strap is configured to maintain a bottle in an upright position regardless of magnet orientation.

Grip strap magnetic mounting device

Some embodiments provide a method of treating skeletal muscular myopathy, e.g., Duchenne muscular dystrophy (DMD), with cardiosphere-derived cells (CDCs), wherein a therapeutically effective amount of CDCs is delivered to a targeted dystrophic skeletal muscle. Some embodiment enable delivery of a therapeutically effective amount of CDCs via intramuscular injection directly at a skeletal muscle or systemic administration, intravenous injection, in a single dose or multiple doses, to treat a targeted dystrophic skeletal muscle. Some embodiments provide a method for improving exercise capabilities in DMD patients. Additional embodiments relate to exosome, mediated transfer of noncoding RNAs ameliorates Duchenne muscular dystrophy by restoring dystrophin in heart and skeletal muscle. Delivery of noncoding RNA species found in CDC-derived exosomes mimics the ability of CDCs and CDC-derived exosomes to increase dystrophin protein levels.

Methods and compositions for treating skeletal muscular dystrophy

Growing community of inventors

Columbus, OH, United States of America

Russell Thomas Rogers