Teikoku Pharma Usa, Inc.

Birch Point Medical, Inc.

Verde Environmental Technologies, Inc.

Travanti Pharma Inc.

Teva Pharmaceuticals International Gmbh

Nupathe Inc.

Russell L Morris

Carter R Anderson

Robert Cohen

Walter L Sembrowich

Terri Sebree

Clayton Anderson

Lori A Grace

William V Fowler

Kathleen A Eischen

Clayton J Anderson

The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.

Abuse potential reduction in abusable substance dosage form

A disposable skin-worn device for the transdermal delivery at least one dose of charged therapeutic substances, including granisetron, by iontophoresis, the device comprising a donor reservoir containing an amount of a therapeutic substance to be delivered transdermally by iontophoresis, a counter reservoir, a source of electric power connected in a circuit between the donor reservoir and the counter reservoir and a control system for controlling current flow in the circuit to enable at least one dose of the therapeutic substance to be delivered transdermally by iontophoresis and wherein the control system includes a control element selected from the group consisting of a sensor activated by an external signal and a switch.

Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis

An integrated iontophoresis skin-worn patch and method for delivering a therapeutically effective amount of a corticosteroid drug compound in a systemically-safe and skin-safe manner for site-specific treatment of inflammation pain is disclosed.

Transdermal methods and systems for the delivery of corticosteroid compounds

Iontophoretic patches for the delivery of anti-migraine compounds and methods of using the patches are described.

Transdermal methods and systems for the delivery of anti-migraine compounds

The potential for environmental release of unused and expired medications is reduced by the provision of a system and method for combining the unused or expired medication with an amount of activated carbon as part of a disposal procedure.

Medication disposal system

A wearable iontophoresis device for the prolonged delivery of a positively charged pharmaceutical species from a salt formulation is disclosed that includes a readily oxidizable metal-based sacrificial anode in the form of a generally planar layer having a connecting area that has a width that is sufficient to insure complete consumption of the oxidizable metal wherein the anode is configured to have a minimum operating life of at least 6 hours under skin-safe conditions, and a drug delivery gel pad in electrical contact with said anode for accommodating a gel containing a positively charged pharmaceutical species in salt form formulated for transdermal delivery.

Sacrificial electrode design and delivery species suitable for prolonged iontophoresis application periods

A transdermal system for the delivery of an anesthetic or other active therapeutic agent directly to a selected site of injured skin tissue by iontophoresis is disclosed, which utilizes a transdermal skin-worn patch including a donor electrode chamber containing a donor electrode and an amount of an active agent in a form suitable for transdermal delivery in electrical communication with the donor electrode and a return electrode. The patch also contains a source of electric current connected in a circuit with the donor and return electrode, a current regulating device is optionally provided in the circuit for controlling the electrical output of the patch and at least the donor electrode chamber includes a provision for absorbing a quantity of fluid associated with weepage from adjacent injured skin tissue.

Growing community of inventors

Lindstrom, MN, United States of America

Russell L Morris