The General Hospital Corporation

The General Hosptial Corporation

Russell L Finley, Jr

Roger Brent

Disclosed are sets of DNA molecules, and cell containing such molecules, each molecule encoding a candidate interacting protein fused to either a DNA binding domain or a gene activating domain to which it is not naturally bonded.

Interaction trap systems for analysis of protein networks

Disclosed are improved methods for detecting protein-protein interactions. These methods involve either a determination of whether three or more proteins are capable of interacting in a trimeric or higher order complex or whether two or more mammalian proteins interact, the latter method utilizing yeast mating to bring candidate proteins into contact with one another.

Growing community of inventors

Belmont, MA, United States of America

Russell L Finley, Jr