Maxygen, Inc.

Other

US Government as Represented by the Secretary of the Army

Russell J Howard

Willem P C Stemmer

Juha Punnonen

Robert Gerald Whalen

Steven Henry Bass

James L Weber

Alan W Thomas

Jeffery A Lyon

Jeffrey L Chulay

This invention provides methods for obtaining molecules that can modulate an immune response, and immunomodulatory molecules obtained using the methods. The molecules find use, for example, in the tailoring of an immune response induced by a genetic vaccine for a desired purpose.

Optimization of immunomodulatory properties of genetic vaccines

This invention is directed to antigen library immunization, which provides methods for obtaining antigens having improved properties for therapeutic and other uses. The methods are useful for obtaining improved antigens that can induce an immune response against pathogens, cancer, and other conditions, as well as antigens that are effective in modulating allergy, inflammatory and autoimmune diseases.

Polynucleotides encoding flavivirus and alphavirus multivalent antigenic polypeptides

Flavivirus and alphavirus recombinant antigen libraries

Antigen library immunization

A multi-chambered portable waste water treatment plant for a mobile home which is installed on or above ground level and can be easily moved from one location to another. The portable waste water treatment plant of the invention is insulated and is internally heated to prevent freezing of the liquids in the plant and promote decomposition of the waste in the plant when ambient temperatures are below freezing.

Portable waste water treatment plant

A method provides peptides that are antigenic determinants identified by antibodies obtained using intact pathogenic agents that present a restricted set of antigens to surveillance by the immune system.

Antigenic determinants recognized by antibodies obtained using a

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Los Altos Hills, CA, United States of America

Russell J Howard