Kibur Medical, Inc.

Ninepoint Medical, Inc.

Russell Hirsch

Christopher J Flaherty

Jason E Fuller

J Christopher Flaherty

Jeffrey S Ross

Robert I Tepper

Jason Fuller

Jessica L Duda

Craig Muir

Described here are devices, systems, and kits for delivering substances to tissues. The devices generally include one or more chambers () and a reservoir () within each chamber. The reservoir may locally deliver a microdose amount of a substance to a target tissue. In some variations, a microdose amount is used in early human studies, e.g., before a phase I clinical trial, to evaluate the effect of the substance on a target tissue, or to obtain pharmacokinetic or metabolic data. In other variations, a microdose amount is used to locally treat a medical condition. In yet other variations, a microdose amount is used to locally deliver a contrast agent for a structural or functional imaging procedure. Methods for delivering and retrieving the devices from the target tissue are also described.

Device and method for drug evaluation and local treatment

Growing community of inventors

Los Altos Hills, CA, United States of America

Russell Hirsch