Other

Eli Lilly and Company

University of East Anglia

Warner-lambert Company

Russell Andrew Lewthwaite

Jason Scott Sawyer

Nicholas J Bach

Stephen Richard Baker

Jeremy Gilmore

Alexander McKillop

George Richard Stephenson

Michael William Urquhart

Alan Daniel Brown

Mark Edward Bunnage

Sham Shridhar Nikam

Paul Alan Glossop

David Anthony Price

David Douglas Manning

Ian Leslie Scott

Brian Edward Kornberg

Michael William John Urquhart

Charlotte Alice Louise Lane

Kim James

The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

Compounds for the treatment of diseases

Piperidine derivatives as subtype selective N-Methyl-D-Aspartate antagonists

This invention relates to a method of making N-benzyl indoles, and to intermediates for use in the method, and to certain substantially optically pure N-benzyl indoles obtained by the method.

Process for preparing N-benzyl indoles

Process for preparing n-benzyl indoles

A process for producing a compound of the formu5la ##STR1## comprising the step of reacting a compound of the formula ##STR2## with a compound of the formula ##STR3## to form a compound of the formula ##STR4## wherein R.sup.2a is selected from the groups recited above for R.sup.2, or R.sup.2a --X-- is a protected hydroxyl group, and Z is a group of formula --Y--R.sub.5 recited above, or a group that can be converted into a group of said formula --Y--R.sup.5. Intermediates of formula IV and composition containing substantially optically pure enantiomers of Formula (I) are included within the scope of the invention.

Growing community of inventors

Cambridge, United Kingdom

Russell Andrew Lewthwaite