Prelude Therapeutics Incorporated

Prelude Therapeutis Incorporated

Rupa Shetty

Andrew Paul Combs

Liang Lu

Michael Hawkins

Juan Luengo

Hong Lin

Gisela Saborit Villarroya

Chaofeng Dai

Klare Lazor Bersch

Philip Michael Pitis

Song Mei

Corey Howard Basch

Raul Andrew Leal

Danielle Julie Beam

John A Rose

The disclosure is directed to, in part, to CDK inhibitors, pharmaceutical compositions comprising the same, as well as methods of their use and preparation.

CDK inhibitors and their use as pharmaceuticals

The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.

Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

The present disclosure provides bifunctional compounds comprising a target protein binding moiety and a E3 ubiquitin ligase binding moiety, and associated methods of use.

BRM targeting compounds and associated methods of use

The disclosure is directed to methods of treatment using compounds of Formula (I).

Growing community of inventors

Blue Bell, PA, United States of America

Rupa Shetty